ChemicalBook > CAS DataBase List > (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
- Product Name
- (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
- CAS No.
- 496791-37-8
- Chemical Name
- (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
- Synonyms
- AR C15585;AR-C 155858;AR-C155858;AR C155858;AR-C 155858;AR C15585;inhibit,AR-C155858,Inhibitor,Monocarboxylate Transporter,AR-C-155858,ARC155858,AR C155858;(S)-6-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)-5-(4-hydroxyisoxazolidine-2-carbonyl)-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-;4-Isoxazolidinol, 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl- 1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-, (4S)-
- CBNumber
- CB12554267
- Molecular Formula
- C21H27N5O5S
- Formula Weight
- 461.53
- MOL File
- 496791-37-8.mol
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(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Property
- Melting point:
- 198-202∶C
- Boiling point:
- 763.1±70.0 °C(Predicted)
- Density
- 1.395
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥52.5 mg/mL in DMSO; ≥57.8 mg/mL in EtOH
- form
- solid
- pka
- 13.53±0.20(Predicted)
- color
- White
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 5.33436
- Product name
- Monocarboxylate Transport Inhibitor, AR-C155858 - CAS 496791-37-8 - Calbiochem
- Packaging
- 5MG
- Price
- $309
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 14884
- Product name
- AR-C 155858
- Packaging
- 1mg
- Price
- $242
- Updated
- 2024/03/01
Tocris
- Product number
- 4960
- Product name
- AR-C155858
- Purity
- ≥98%(HPLC)
- Packaging
- 1
- Price
- $209
- Updated
- 2021/12/16
Usbiological
- Product number
- 001552
- Product name
- AR-C155858
- Packaging
- 1mg
- Price
- $496
- Updated
- 2021/12/16
TRC
- Product number
- A187720
- Product name
- AR-C155858
- Packaging
- 1mg
- Price
- $195
- Updated
- 2021/12/16
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(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Chemical Properties,Usage,Production
Uses
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10.
storage
Store at -20°C
(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Preparation Products And Raw materials
Raw materials
Preparation Products
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