ChemicalBook > CAS DataBase List > 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine

Product Name: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine
CAS No.: 916176-52-8
Chemical Name: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine
Synonyms: 4-BroMo-5-chloro-7-azaindole;4-Bromo-5-chloro-1H-pyrrolo[2;4-BroMo-5-chloro-7-aza-1H-indole;4-BroMo-5-chloro-7-aza-2H-indole;4-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine;1H-pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-
CBNumber: CB12554717
Molecular Formula: C7H4BrClN2
Formula Weight: 231.48
MOL File: 916176-52-8.mol

Less

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine Property

Density: 1.878
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 12.04±0.40(Predicted)
Appearance: Off-white to pink Solid

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 1548AQ
Product name: 4-BROMO-5-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
Packaging: 100mg
Price: $258.8
Updated: 2021/12/16

AK Scientific

Product number: 1548AQ
Product name: 4-BROMO-5-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
Packaging: 1g
Price: $1143.2
Updated: 2021/12/16

Ambeed

Product number: A296012
Product name: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine
Purity: 95%
Packaging: 5g
Price: $1250
Updated: 2021/12/16

Crysdot

Product number: CD11017227
Product name: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine
Purity: 95+%
Packaging: 5g
Price: $1386
Updated: 2021/12/16

Alichem

Product number: 916176528
Product name: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 5g
Price: $1503.48
Updated: 2021/12/16

Less

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Usage,Production

Uses

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine can be used in drug synthesis and as a pharmaceutical intermediate in scientific research.

Synthesis

916176-51-7

916176-52-8

5-Chloro-1H-pyrrolo[2,3-b]pyridine-7-oxide (5.00 g, 29.66 mmol) was used as a raw material, which was dissolved with tetrabutylammonium bromide (Bu4Br, 19.12 g, 59.31 mmol) in N,N-dimethylformamide (DMF, 200 mL). Trifluoromethanesulfonic anhydride (Tf2O, 20.91 g, 74.20 mmol) was slowly added dropwise to the above solution at 0 °C. After the dropwise addition, the reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction solution was poured into water (500 mL), and the pH of the mixture was adjusted to 8-9 with saturated aqueous sodium bicarbonate (NaHCO3). The precipitate was collected by filtration, and the filter cake was washed with water (50 mL x 3) and dried under vacuum at 60 °C overnight to afford 4-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine as an off-white solid (5.83 g, yield 84.9%). Mass spectrum (ESI, positive ion mode) m/z: 231.0 [M + H]+; NMR hydrogen spectrum (400 MHz, DMSO-d6) δ (ppm): 12.24 (s, 1H), 8.30 (s, 1H), 7.68 (s, 1H), 6.45 (s, 1H).

References

[1] Patent: WO2018/169700, 2018, A1. Location in patent: Paragraph 00328; 00329
[2] Patent: US2010/81645, 2010, A1. Location in patent: Page/Page column 37
[3] Patent: WO2006/127587, 2006, A1. Location in patent: Page/Page column 87

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine Suppliers

China 52 India 1 United Kingdom 1 United States 3 Global 57

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Wuhan ariel chemical Co., LTD.

Tel: 18986259541
Fax: 027-87840182
Email: sales@3stc.com
Country: China
ProdList: 3764
Advantage: 58

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Wuhan Kaymke Chemical Co., Ltd.,

Tel: 027-027-87342388 18086026008
Fax: 027-87342388
Email: sales@kaymke.com
Country: China
ProdList: 3731
Advantage: 55

Shanghai Devinchem Ltd

Tel: 027-65318838 13646286950
Email: sales@devinchem.com
Country: China
ProdList: 2953
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Jiaxing Novartis Chemical Co., Ltd.

Tel: 18957373295
Fax: -
Country: China
ProdList: 1580
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing KaiMubo Pharmaceutical Co., Ltd.

Tel: 025-66162170
Fax: 025-66162170
Country: China
ProdList: 7181
Advantage: 55

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9756
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9717
Advantage: 58

ShangHai Book Chemical Co., Ltd.

Tel: 15001988657 15802146997
Email: info@bookchemicals.com
Country: China
ProdList: 950
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8645
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

KARMEL TECHNOLOGY (HK) CO.,LIMITED

Tel: +8618795957998
Email: karmelhk@126.com
Country: CHINA
ProdList: 2886
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7448
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9990
Advantage: 58

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7587
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Zhengzhou Paihe Tade Pharmaceutical Technology Co., Ltd.

Tel: 13343718483
Email: 2705696146@qq.com
Country: China
ProdList: 308
Advantage: 58

Birdo (Shanghai) Medical Technology Co., Ltd.

Tel: 021-58099077-8041 18601625411
Email: sales@birdotech.com
Country: China
ProdList: 9764
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Beijing InnoChem Science & Technology Co., Ltd.

Tel: 15652467323
Email: sales@inno-chem.com.cn
Country: China
ProdList: 8293
Advantage: 58

Shaanxi Didu New Material Co., Ltd

Tel: 029-81145920 17391631969
Email: 1046@dideu.com
Country: China
ProdList: 9996
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Huasige Pharmaceutical Technology Co., LTD

Tel: 13611612777
Email: 3627377363@qq.com
Country: China
ProdList: 4015
Advantage: 58

Suzhou Qihang Biotechnology Co., Ltd

Tel: 18151111370
Email: 1046215251@qq.com
Country: China
ProdList: 8718
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188 13327728092
Email: sales@pharmablock.com
Country: China
ProdList: 10000
Advantage: 58

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c6@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd

Tel: 029-81310890 18165209495
Email: 2929288192@qq.com
Country: China
ProdList: 9729
Advantage: 58

Changzhou Book Chemical Co., Ltd.

Tel: 13606129753 13775119556
Fax: 0519-68780180
Email: bookchem@126.com
Country: China
ProdList: 1585
Advantage: 62

Guangzhou Reullei Pharmaceutical Technology Co., Ltd，

Tel: 13660253774
Email: joe.yang@reullei.com
Country: China
ProdList: 4994
Advantage: 58

Elucigen bio

Tel: 13501719342; 13501719342
Email: wayne.zheng@elucigenbio.com
Country: China
ProdList: 5000
Advantage: 58

Shanghai Hanhong Scientific Co., Ltd.

Tel: +undefined17612118332
Email: Lucky@hanhonggroup.com
Country: China
ProdList: 5844
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Sichuan Biosynce Pharmatech Co., Ltd.

Tel: +8619950309693
Email: diane@biosynce.com
Country: China
ProdList: 4871
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Chemia Biotechnology（Shanghai） Co., Ltd

Tel: +8613816753574
Email: info@chemia-pharm.com
Country: CHINA
ProdList: 311
Advantage: 58

Less

View Lastest Price from 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine manufacturers

Career Henan Chemical Co

Product: 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine 916176-52-8
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2020-01-10

916176-52-8, 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridineRelated Search:

4-BroMo-5-chloro-7-aza-1H-indole

1H-pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-

4-BroMo-5-chloro-7-azaindole

4-Bromo-5-chloro-1H-pyrrolo[2

4-BroMo-5-chloro-7-aza-2H-indole

4-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine

916176-52-8