N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine

Product Name: N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine
CAS No.: 232271-19-1
Chemical Name: N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine
Synonyms: MDK1191;MDK-1191;TR 14035;TR-14035;TR 14035;TR14035;TR 14035;TR14035;MDK-1191;MDK1191;N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine;(S)-2-(2,6-DichlorobenzaMido)-3-(2',6'-diMethoxy-[1,1'-biphenyl]-4-yl)propanoic acid;(S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid;[1,1'-Biphenyl]-4-propanoic acid, α-[(2,6-dichlorobenzoyl)amino]-2',6'-dimethoxy-, (αS)-;(alphaS)-alpha-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy-[1,1'-biphenyl]-4-propanoic acid
CBNumber: CB12565722
Molecular Formula: C24H21Cl2NO5
Formula Weight: 474.33
MOL File: 232271-19-1.mol

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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Property

Boiling point:: 604.0±55.0 °C(Predicted)
Density: 1.333
storage temp.: 2-8°C
solubility: DMSO: ≥ 41 mg/mL (86.44 mM)
form: Powder
pka: 3.53±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6908
Product name: TR14035
Purity: ≥98%(HPLC)
Packaging: 50
Price: $905
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573451
Product name: TR-14035
Purity: >98%
Packaging: 100mg
Price: $1060.8
Updated: 2021/12/16

ChemScene

Product number: CS-1812
Product name: TR-14035
Purity: 95.14%
Packaging: 50mg
Price: $1080
Updated: 2021/12/16

Activate Scientific

Product number: AS43383
Product name: TR 14035
Purity: 98% ee
Packaging: 5mg
Price: $145
Updated: 2021/12/16

Activate Scientific

Product number: AS43383
Product name: TR 14035
Purity: 98% ee
Packaging: 25mg
Price: $286
Updated: 2021/12/16

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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Chemical Properties,Usage,Production

Biological Activity

TR-14035 (SB 683698, MDK-1191) is a dual alpha4beta (α4β) integrin antagonist with IC50 values of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.

in vitro

TR-14035 blocks adhesion of RPMI-8866 cells to MAdCAM-Ig by 100% at 1 μM, with an approximate IC ₅₀ of 0.01 μM.

target

Target	Value
α4β7 (Cell-free assay)	7 nM
α4β1 (Cell-free assay)	87 nM

storage

Store at -20°C

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Suppliers

China 45 India 1 United Kingdom 1 United States 10 Global 57

Shanghai Boyle Chemical Co., Ltd.

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Shanghai Feibo Chemical Technology Co., Ltd

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Shanghai Topbiochem Technology Co., Ltd

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Haoyuan Chemexpress Co., Ltd.

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MedChemexpress LLC

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LETOPHARM LIMITED

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SPIRO PHARMA

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Guangzhou QiYun Biotechnology Co., Ltd.

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Tianjin Kailiqi Biotechnology Co., Ltd.

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232271-19-1, N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanineRelated Search:

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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine

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232271-19-1