Magnesium Orotate

ChemicalBook > CAS DataBase List > Magnesium Orotate

Product Name: Magnesium Orotate
CAS No.: 34717-03-8
Chemical Name: Magnesium Orotate
Synonyms: TUBB3;CDCBM;TUBB4;CFEOM3A;beta-4)-;Tubulin β-4;Tubulin β-III;tubulin, beta 3;Tubulin β-3 chain;MAGNESIUM OROTATE
CBNumber: CB1257706
Molecular Formula: C10H4MgN4O8
Formula Weight: 332.47
MOL File: 34717-03-8.mol

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Magnesium Orotate Property

storage temp.: -20°C
InChI: InChI=1S/2C5H4N2O4.Mg/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H3,6,7,8,9,10,11);/q;;+4/p-4
InChIKey: MEZKYWVZYGZEHX-UHFFFAOYSA-J
SMILES: O=C1NC(=O)C=C2C(=O)[O-][Mg+2]3([O-]C(=O)C4=CC(=O)NC(=O)N34)N12
LogP: -0.928 (est)
EPA Substance Registry System: Magnesium, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-.kappa.N3,.kappa.O4)-, (T-4)- (34717-03-8)

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 142656
Product name: Tubulin Beta 3
Packaging: 200ul
Price: $446
Updated: 2021/12/16

Usbiological

Product number: T9155-11
Product name: Tubulin, beta 3
Packaging: 200ug
Price: $736
Updated: 2021/12/16

Matrix Scientific

Product number: 059672
Product name: Magnesium bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate)
Packaging: 500mg
Price: $199
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb528408
Product name: TUBB3
Packaging: 10μg
Price: $290.7
Updated: 2021/12/16

AK Scientific

Product number: X4062
Product name: Magnesiumorotate
Packaging: 500mg
Price: $318
Updated: 2021/12/16

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Magnesium Orotate Chemical Properties,Usage,Production

Description

Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers. Experiments investigating the potential cardioprotective actions of orotic acid in pathological heart conditions are still ongoing.

Uses

magnesium orotate is used as an adjuvant treatment in congestive heart failure, hyperten-sion, post-operative cardiac status or in type 2 diabetes.
Magnesium orotate combines in itself the cardio protective properties of magnesium and orotic acid and leads to the optimisation of the magnesium effect by reducing cellular magnesium loss.
At the same time, animal studies have indicated a protective effect of magnesium orotate with respect to atherosclerotic vascular changes. The efficacy of the combination was superior to the effect of the individual components of magnesium and orotic acid.

Preparation

For the synthesis of magnesium orotate and due to the low solubility of both magnesium hydroxide and orotic acid, 50 mL H2O were heated up to 70 °C. Half of the magnesium hydroxide (total: 0.125 g, 2.16 mmol, 1 eq.) was added to the warm solution. Subsequently, small amounts of both orotic acid (total: 0.75 g, 4.31 mmol, 2 eq.) and the remaining magnesium hydroxide were added alternatingly. After heating the solution to 90 °C and stirring it for 30 min, it was stored in the fridge for crystallization. After one weekend, 0.70 g (1.46 mmol, 68 %) of a white microcrystalline material could be obtained after filtration and drying.

IR, NMR and PXRD analysis (presented in sections S2 and S4) confirmed the product to be magnesium orotate octahydrate.

Magnesium Orotate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Magnesium Orotate manufacturers

Hebei Guanlang Biotechnology Co., Ltd.

Product: MAGNESIUM OROTATE 34717-03-8
Price: US $10.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-03-11

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Magnesium Orotate 34717-03-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-23

Hebei Kingfiner Technology Development Co.Ltd

Product: Magnesium Orotate 34717-03-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 50000kg
Release date: 2024-05-15

34717-03-8, Magnesium OrotateRelated Search:

Orotic acid Magnesium carbonate Magnesium stearate kavaform Magnesium Orotate

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