ChemicalBook > CAS DataBase List > KOdiA-PC

KOdiA-PC

Product Name
KOdiA-PC
CAS No.
439904-33-3
Chemical Name
KOdiA-PC
Synonyms
KOdiA-PC;KOdiA-PC Exclusive;PEZXEQJZQAVYCZ-NLMPBQEBSA-N
CBNumber
CB12591541
Molecular Formula
C32H58NO11P
Formula Weight
663.79
MOL File
439904-33-3.mol
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KOdiA-PC Property

storage temp. 
Store at -80°C, protect from light
solubility 
DMF: .5 mg/ml; DMSO: .5 mg/ml; Ethanol: 30 mg/ml; PBS (pH7.2): 5 mg/ml
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
62945
Product name
KOdiA-PC
Purity
≥98%
Packaging
500μg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
62945
Product name
KOdiA-PC
Purity
≥98%
Packaging
1mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
62945
Product name
KOdiA-PC
Purity
≥98%
Packaging
5mg
Price
$412
Updated
2024/03/01
Cayman Chemical
Product number
62945
Product name
KOdiA-PC
Purity
≥98%
Packaging
10mg
Price
$711
Updated
2024/03/01
AK Scientific
Product number
1106AH
Product name
1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine
Packaging
10mg
Price
$889
Updated
2021/12/16
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KOdiA-PC Chemical Properties,Usage,Production

Description

Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.1 Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position.2 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine, or KOdiA-PC, is one of the most potent CD36 ligands among the oxLDL species.3 KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle, and may be one of the more important structural determinants of oxLDL.

Definition

ChEBI: PKODiA-PC is a 1,2-diacyl-sn-glycero-3-phosphocholine.

References

1. Podrez, E.A., Febbraio, M., Sheibani, N., et al. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species J. Clin. Invest. 105(8),1095-1108(2000).
2. Podrez, E.A., Poliakov, E., Shen, Z., et al. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions J. Biol. Chem. 277(41),38517-38523(2002).
3. Podrez, E.A., Poliakov, E., Shen, Z., et al. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36 J. Biol. Chem. 277(41),38503-38516(2002).

KOdiA-PC Preparation Products And Raw materials

Raw materials

Preparation Products

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KOdiA-PC Suppliers

China 27 United States 2 Global 29
Shanghai Changyu Medical Technology Co. Ltd.
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439904-33-3, KOdiA-PCRelated Search:


  • KOdiA-PC
  • KOdiA-PC Exclusive
  • PEZXEQJZQAVYCZ-NLMPBQEBSA-N
  • 439904-33-3