1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE

Product Name: 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE
CAS No.: 165377-43-5
Chemical Name: 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE
Synonyms: AGY 94806;CutaMesine;Cutamesine (SA 4503;1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine;1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE;Piperazine, 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-
CBNumber: CB12614118
Molecular Formula: C23H32N2O2
Formula Weight: 368.51
MOL File: 165377-43-5.mol

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1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE Property

Boiling point:: 499.2±45.0 °C(Predicted)
Density: 1.053±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO
pka: 7.61±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: 4134CR
Product name: Cutamesine
Packaging: 50mg
Price: $170
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0096836
Product name: 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL) PIPERAZINE
Purity: 95.00%
Packaging: 5MG
Price: $503.02
Updated: 2021/12/16

Ambeed

Product number: A606126
Product name: SA4503
Purity: 98%
Packaging: 100mg
Price: $662
Updated: 2021/12/16

CSNpharm

Product number: CSN17988
Product name: SA4503
Packaging: 10mg
Price: $113
Updated: 2021/12/16

Crysdot

Product number: CD31003075
Product name: SA4503
Purity: 98+%
Packaging: 25mg
Price: $252
Updated: 2021/12/16

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1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE Chemical Properties,Usage,Production

Uses

Cutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor (IC50= 17.4±1.9 nM); 100-fold less affinity for the sigma 2 receptor.

IC 50

Sigma 1 Receptor

References

[1] Matsuno K, et al. Binding properties of SA4503, a novel and selective sigma 1 receptor agonist. Eur J Pharmacol. 1996 Jun 13;306(1-3):271-9. DOI:10.1016/0014-2999(96)00201-4
[2] Minabe Y, et al. Acute and chronic administration of the selective sigma1 receptor agonist SA4503 significantly alters the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study. Synapse. 1999 Aug;33(2):129-40. DOI:10.1002/(SICI)1098-2396(199908)33:23.0.CO;2-E
[3] Ono Y, et al. SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models. Neurosci Lett. 2014 Jan 24;559:174-8. DOI:10.1016/j.neulet.2013.12.005

1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE Suppliers

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165377-43-5, 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINERelated Search:

2-Methoxyphenylacetic acid 4'-Hydroxyacetophenone Sodium benzoate

1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-(3-PHENYLPROPYL)PIPERAZINE

AGY 94806

CutaMesine

1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine

Piperazine, 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-

Cutamesine (SA 4503

165377-43-5