ChemicalBook > CAS DataBase List > Polygalacin D

Polygalacin D

Product Name
Polygalacin D
CAS No.
66663-91-0
Chemical Name
Polygalacin D
Synonyms
Onjisaponin D;Polygalacin D;Polygalacin D2;Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-
CBNumber
CB12614224
Molecular Formula
C57H92O27
Formula Weight
1209.34
MOL File
66663-91-0.mol
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Polygalacin D Property

Density 
1.54±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
4°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
12.76±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
300806
Product name
Polygalacin D
Packaging
10mg
Price
$632
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259443
Product name
Polygalacin D
Purity
98%
Packaging
5mg
Price
$433.5
Updated
2021/12/16
ChemScene
Product number
CS-0032282
Product name
PolygalacinD
Purity
99.30%
Packaging
5mg
Price
$457
Updated
2021/12/16
ChemScene
Product number
CS-0032282
Product name
PolygalacinD
Purity
99.30%
Packaging
1mg
Price
$152
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259443
Product name
Polygalacin D
Purity
98%
Packaging
10mg
Price
$591.6
Updated
2021/12/16
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Polygalacin D Chemical Properties,Usage,Production

Chemical Properties

White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

Definition

ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway.

target

NOS | COX | PGE | NO | NF-kB

Polygalacin D Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polygalacin D manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Polygalacin D 66663-91-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-28
Shanghai Standard Technology Co., Ltd.
Product
Polygalacin D 66663-91-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-03
Career Henan Chemical Co
Product
Polygalacin D 66663-91-0
Price
US $16.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 10kg, 50kg
Release date
2020-03-09