(+)-Blebbistatin

Product Name: (+)-Blebbistatin
CAS No.: 1177356-70-5
Chemical Name: (+)-Blebbistatin
Synonyms: (+)Blebbistatin,(+) Blebbistatin;(+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem;(3aR)-3a-hydroxy-6-methyl-1-phenyl-1H,2H,3H,3aH,4H-pyrrolo[2,3-b]quinolin-4-one;4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-
CBNumber: CB12620724
Molecular Formula: C18H16N2O2
Formula Weight: 292.33
MOL File: 1177356-70-5.mol

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(+)-Blebbistatin Property

Boiling point:: 507.3±60.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: -20C
solubility: DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12.5 mg/ml
form: Yellow solid
pka: 11.15±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 203392
Product name: (+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem
Purity: The inactive enantiomer of (±)-Blebbistatin.
Packaging: 1mg
Price: $172
Updated: 2024/03/01

Cayman Chemical

Product number: 13165
Product name: (+)-Blebbistatin
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 13165
Product name: (+)-Blebbistatin
Purity: ≥98%
Packaging: 5mg
Price: $151
Updated: 2024/03/01

Cayman Chemical

Product number: 13165
Product name: (+)-Blebbistatin
Purity: ≥98%
Packaging: 10mg
Price: $283
Updated: 2024/03/01

Cayman Chemical

Product number: 13165
Product name: (+)-Blebbistatin
Purity: ≥98%
Packaging: 25mg
Price: $618
Updated: 2024/03/01

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(+)-Blebbistatin Chemical Properties,Usage,Production

Chemical Properties

Bright Yellow Solid

Uses

Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100μM. A negative control for the (S)-(-)-Blebblastatin. [a]D= +110 (c= 1.21 CHCl3) (±)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one Selective inhibitor of nonmuscle myosin II; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.

Definition

ChEBI: (R)-blebbistatin is the (R)-enantiomer of blebbistatin. It is a blebbistatin and a tertiary alpha-hydroxy ketone.

storage

Store at +4°C

(+)-Blebbistatin Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Blebbistatin Suppliers

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1177356-70-5, (+)-BlebbistatinRelated Search:

(+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem

4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-

(+)Blebbistatin,(+) Blebbistatin

(3aR)-3a-hydroxy-6-methyl-1-phenyl-1H,2H,3H,3aH,4H-pyrrolo[2,3-b]quinolin-4-one

1177356-70-5

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