2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe

Product Name: 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
CAS No.: 17302-61-3
Chemical Name: 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
Synonyms: 1-oxime;PoloxiMe;5-Cyclohexadiene-1;2-methyl-5-(1-methylethyl)-;p-Mentha-3,6-diene-2,5-dione 2-oxime;2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
CBNumber: CB12623846
Molecular Formula: C10H13NO2
Formula Weight: 179.22
MOL File: 17302-61-3.mol

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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Property

Melting point:: 162℃ (Decomposition)
Boiling point:: 296.8±33.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 6.43±0.58(Predicted)
form: Powder
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A102086
Product name: Poloxime
Packaging: 100mg
Price: $220
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611818
Product name: Poloxime
Packaging: 10mg
Price: $221
Updated: 2021/12/16

ChemScene

Product number: CS-1334
Product name: Poloxime
Packaging: 5mg
Price: $78
Updated: 2021/12/16

ApexBio Technology

Product number: B3609
Product name: Poloxime
Packaging: 10mg
Price: $166
Updated: 2021/12/16

ApexBio Technology

Product number: B3609
Product name: Poloxime
Packaging: 5mg
Price: $103
Updated: 2021/12/16

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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Chemical Properties,Usage,Production

Biological Activity

Poloxime is a hydrolysis product of poloxin, a non-competitive ATP inhibitor of Plk1, which can properly inhibit the activity of Plk1.

in vitro

Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1).

target

PLK1

2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Preparation Products And Raw materials

Raw materials

Preparation Products

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17302-61-3, 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMeRelated Search:

2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe

PoloxiMe

p-Mentha-3,6-diene-2,5-dione 2-oxime

1-oxime

2-methyl-5-(1-methylethyl)-

5-Cyclohexadiene-1

17302-61-3