ChemicalBook > CAS DataBase List > 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Product Name
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CAS No.
1256584-80-1
Chemical Name
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Synonyms
181484;Alectinib Impurity 12;9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile;9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile;9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile;5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-;9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile-11
CBNumber
CB12624065
Molecular Formula
C21H17IN2O
Formula Weight
440.28
MOL File
1256584-80-1.mol
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9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Property

Melting point:
>300°C
Boiling point:
612.0±55.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.47±0.40(Predicted)
color 
White to Off-White
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E918370
Product name
9-​Ethyl-​8-​iodo-​6,​6-​dimethyl-​11-​oxo-​6,​11-​dihydro-​5H-​benzo[b]​carbazole-​3-​carbonitrile
Packaging
250mg
Price
$125
Updated
2021/12/16
TRC
Product number
E918370
Product name
9-​Ethyl-​8-​iodo-​6,​6-​dimethyl-​11-​oxo-​6,​11-​dihydro-​5H-​benzo[b]​carbazole-​3-​carbonitrile
Packaging
1g
Price
$460
Updated
2021/12/16
ChemScene
Product number
CS-M1357
Product name
9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Packaging
250mg
Price
$523
Updated
2021/12/16
ChemScene
Product number
CS-M1357
Product name
9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Packaging
100mg
Price
$314
Updated
2021/12/16
Alichem
Product number
1256584801
Product name
9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Packaging
250mg
Price
$452.76
Updated
2021/12/16
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9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Chemical Properties,Usage,Production

Uses

9-?Ethyl-?8-?iodo-?6,?6-?dimethyl-?11-?oxo-?6,?11-?dihydro-?5H-?benzo[b]?carbazole-?3-?carbonitrile is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Process impurity.

9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Suppliers

Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
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021-34666753 13311639313
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+86-21-34979012
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(86) 21-58955996
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UHN Shanghai Research & Development Co., Ltd.
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+86 (21) 5895-8628
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Shanghai AQBioPharma Co., Ltd.
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Shanghai Synchem Pharma Co., ltd
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21-619849051-1 18521059765
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synchempharma@aliyun.com
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China
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SPIRO PHARMA
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China
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SPIRO PHARMA
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View Lastest Price from 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile manufacturers

Career Henan Chemical Co
Product
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile 1256584-80-1
Price
US $1.00/KG
Min. Order
1IU
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

1256584-80-1, 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileRelated Search:


  • 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
  • 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile-11
  • 9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
  • Alectinib Impurity 12
  • 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
  • 181484
  • 5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-
  • 1256584-80-1