3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-

Product Name: 3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-
CAS No.: 875634-01-8
Chemical Name: 3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-
Synonyms: PPY A;5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide;5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide;3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-
CBNumber: CB12626827
Molecular Formula: C22H20N4O2
Formula Weight: 372.42
MOL File: 875634-01-8.mol

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3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl- Property

Density: 1.248±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: <37.24mg/ml in DMSO
pka: 12.93±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 4730
Product name: PPYA
Purity: ≥98%(HPLC)
Packaging: 10
Price: $261
Updated: 2021/12/16

Tocris

Product number: 4730
Product name: PPYA
Purity: ≥98%(HPLC)
Packaging: 50
Price: $1056
Updated: 2021/12/16

Usbiological

Product number: 256316
Product name: PPY A
Packaging: 10mg
Price: $516
Updated: 2021/12/16

ApexBio Technology

Product number: A8607
Product name: PPYA
Packaging: 50mg
Price: $1568
Updated: 2021/12/16

ApexBio Technology

Product number: A8607
Product name: PPYA
Packaging: 10mg
Price: $385
Updated: 2021/12/16

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3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl- Chemical Properties,Usage,Production

Uses

PPY-A is a potent T315I mutant and wild-type Abl kinases inhibitor with IC50s of 9 and 20 nM, respectively. PPY-A inhibits BaF3 cells transformed with wild-type Abl and Abl T315I mutantl with IC50s of 390 and 180 nM, respectively. PPY-A can be used for the research of chronic myeloid leukemia (CML)[1].

storage

Store at -20°C

References

[1] Tianjun Zhou, et al. Crystal structure of the T315I mutant of AbI kinase. Chem Biol Drug Des. 2007 Sep;70(3):171-81. DOI:10.1111/j.1747-0285.2007.00556.x

3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl- Suppliers

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875634-01-8, 3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-Related Search:

5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide

3-PyridinecarboxaMide, 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-diMethyl-

PPY A

5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide

875634-01-8