BI605906

ChemicalBook > CAS DataBase List > BI605906

Product Name: BI605906
CAS No.: 960293-88-3
Chemical Name: BI605906
Synonyms: CS-2032;BI605906;BI-605906,BI605906;3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide;3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide;3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide;Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-
CBNumber: CB12627596
Molecular Formula: C17H22F2N4O3S2
Formula Weight: 432.51
MOL File: 960293-88-3.mol

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BI605906 Property

Boiling point:: 713.7±60.0 °C(Predicted)
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Acetonitrile: 1 mg/ml; DMSO: 30 mg/ml
form: A crystalline solid
pka: 16.18±0.30(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3370
Product name: BI605906
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $92.8
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML3370
Product name: BI605906
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $375
Updated: 2023/06/20

Cayman Chemical

Product number: 19184
Product name: BI-605906
Purity: ≥98%
Packaging: 1mg
Price: $76
Updated: 2024/03/01

Cayman Chemical

Product number: 19184
Product name: BI-605906
Purity: ≥98%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 19184
Product name: BI-605906
Purity: ≥98%
Packaging: 10mg
Price: $317
Updated: 2024/03/01

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BI605906 Chemical Properties,Usage,Production

Uses

BI 605906, is a novel inhibitors of the kappa B kinase subunit β (IKKβ; IC50 = 380 nM).

Biological Activity

BI605906 is a selective, ATP-competitive IKB kinase β (IKK2, IKKβ, IKK-beta) inhibitor (IC50 = 380 nM, [ATP] = 0.1 mM) with no potency toward 100 other kinases, including IKKα, IKKε, TBK1, and IGF1R (IC50 ≥7.6 μM). BI605906 (10 μM) effectively blocks IKK-β-dependent phosphorylation of IKKε and TBK1 in IKKα-/- MEFs upon IL-1α (5 ng/mL) induction.

storage

Store at -20°C

BI605906 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI605906 Suppliers

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960293-88-3, BI605906Related Search:

BI605906

3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide

3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide

CS-2032

Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-

BI-605906,BI605906

3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide

960293-88-3

C17H22F2N4O3S2

Inhibitor