DWK-1339

Product Name: DWK-1339
CAS No.: 1018946-38-7
Chemical Name: DWK-1339
Synonyms: SNU-0039;DWK-1339;SNU-0039 (DWK-133);DWK-1339;DWK 1339;DWK1339;2-(3,4-dimethoxyphenyl)-5-(3-methoxypropyl)-1-benzofuran;Benzofuran, 2-(3,4-diMethoxyphenyl)-5-(3-Methoxypropyl)-;2-(3,4-DiMethoxy-phenyl)-5-(3-Methoxy-propyl)-benzofuran;MDR1339,DWK1339,inhibit,β-amyloid peptide,Inhibitor,MDR 1339,Abeta,Amyloid-β,MDR-1339,DWK 1339
CBNumber: CB12627783
Molecular Formula: C20H22O4
Formula Weight: 326.39
MOL File: 1018946-38-7.mol

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DWK-1339 Property

storage temp.: Store at -20°C
solubility: DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 2mg/mL
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27642
Product name: DWK-1339
Packaging: 500μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 27642
Product name: DWK-1339
Packaging: 5mg
Price: $722
Updated: 2024/03/01

Cayman Chemical

Product number: 27642
Product name: DWK-1339
Packaging: 1mg
Price: $230
Updated: 2024/03/01

TRC

Product number: D103595
Product name: DWK-1339
Packaging: 1mg
Price: $275
Updated: 2021/12/16

ChemScene

Product number: CS-0003407
Product name: MDR-1339
Purity: 98.03%
Packaging: 5mg
Price: $165
Updated: 2021/12/16

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DWK-1339 Chemical Properties,Usage,Production

Description

DWK-1339 is an inhibitor of amyloid-β (Aβ) aggregation. It inhibits aggregation of monomeric Aβ (1-42) (Aβ42) and induces disaggregation of Aβ42 fibrils in vitro when used at concentrations ranging from 3.1 to 50 μM. DWK-1339 (10 μM) reduces Aβ42-induced toxicity in HT-22 cells. In vivo, DWK-1339 (10 mg/kg) increases step-through latency in a passive avoidance test and increases spontaneous alteration in the Y-maze compared with vehicle control mice in a mouse model of Aβ42-induced acute Alzheimer''s disease. It also decreases brain levels of Aβ42 and increases spontaneous alteration in the Y-maze in the APP/PS1 transgenic mouse model of Alzheimer''s disease.

Uses

DWK-1339, is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer''s disease.

DWK-1339 Preparation Products And Raw materials

Raw materials

Preparation Products

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DWK-1339 Suppliers

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1018946-38-7, DWK-1339Related Search:

DWK-1339

2-(3,4-DiMethoxy-phenyl)-5-(3-Methoxy-propyl)-benzofuran

Benzofuran, 2-(3,4-diMethoxyphenyl)-5-(3-Methoxypropyl)-

2-(3,4-dimethoxyphenyl)-5-(3-methoxypropyl)-1-benzofuran

DWK-1339;DWK 1339;DWK1339

SNU-0039

SNU-0039 (DWK-133)

MDR1339,DWK1339,inhibit,β-amyloid peptide,Inhibitor,MDR 1339,Abeta,Amyloid-β,MDR-1339,DWK 1339

1018946-38-7

1018964-38-7