SR3335

Product Name: SR3335
CAS No.: 293753-05-6
Chemical Name: SR3335
Synonyms: ML-176;SR3335;SR3335;ML176;ML-176;SR-3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR 3335 (This product is only available in Japan.);N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
CBNumber: CB12628427
Molecular Formula: C13H9F6NO3S2
Formula Weight: 405.3358792
MOL File: 293753-05-6.mol

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SR3335 Property

storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO
form: solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2820
Product name: SR3335
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $94.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2820
Product name: SR3335
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $381
Updated: 2024/03/01

Cayman Chemical

Product number: 12072
Product name: SR 3335
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 12072
Product name: SR 3335
Purity: ≥95%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 12072
Product name: SR 3335
Purity: ≥95%
Packaging: 10mg
Price: $186
Updated: 2024/03/01

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SR3335 Chemical Properties,Usage,Production

Description

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (K_i = 220 nM) and inhibiting constitutive transactivation activity (IC₅₀ = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.

Definition

ChEBI: N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-thiophenesulfonamide is a sulfonamide.

target

RORα

SR3335 Preparation Products And Raw materials

Raw materials

Preparation Products

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SR3335 Suppliers

China 62 India 1 Japan 1 United States 10 Global 74

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View Lastest Price from SR3335 manufacturers

Career Henan Chemical Co

Product: SR3335 293753-05-6
Price: US $9.80/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2019-12-21

293753-05-6, SR3335Related Search:

SR3335

SR3335,Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide

ML-176

N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide

hiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide

ML-176;SR-3335

SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176

SR3335;ML176

SR 3335 (This product is only available in Japan.)

Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide

ML-176;SR 3335;SR-3335;ML176;ML 176

2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-

N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide

293753-05-6

C13H9F6NO3S2