Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-

Product Name: Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-
CAS No.: 367273-07-2
Chemical Name: Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-
Synonyms: NRX-195183;AGN195183,AGN 195183;IRX5183 (NRX195183, VTP195183, AGN195183);Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-
CBNumber: CB12631739
Molecular Formula: C22H22ClF2NO4
Formula Weight: 437.86
MOL File: 367273-07-2.mol

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Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro- Property

Boiling point:: 500.9±50.0 °C(Predicted)
Density: 1.354±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: ≥ 62 mg/mL (141.60 mM)
form: Solid
pka: 2.36±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3203
Product name: AGN195183
Purity: 99.26%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-3203
Product name: AGN195183
Purity: 99.26%
Packaging: 10mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-3203
Product name: AGN195183
Purity: 99.26%
Packaging: 25mg
Price: $900
Updated: 2021/12/16

ChemScene

Product number: CS-3203
Product name: AGN195183
Purity: 99.26%
Packaging: 50mg
Price: $1350
Updated: 2021/12/16

Crysdot

Product number: CD31002076
Product name: AGN195183
Purity: 98+%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

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Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro- Chemical Properties,Usage,Production

Uses

AGN-195183 (IRX-5183) is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836. AGN-195183 has no activity on RARβ/γ.

References

[1] Beard RL, et al. Synthesis and biological activity of retinoic acid receptor-alpha specific amides. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3145-8. DOI:10.1016/s0960-894x(02)00647-9

Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro- Preparation Products And Raw materials

Raw materials

Preparation Products

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367273-07-2, Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-Related Search:

Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-

IRX5183 (NRX195183, VTP195183, AGN195183)

AGN195183,AGN 195183

NRX-195183

367273-07-2

C22H22ClF2NO4