5-broMo-2,4-diMethyl-pyriMidine
- Product Name
- 5-broMo-2,4-diMethyl-pyriMidine
- CAS No.
- 69696-37-3
- Chemical Name
- 5-broMo-2,4-diMethyl-pyriMidine
- Synonyms
- 5-broMo-2,4-diMethyl-pyriMidine;Pyrimidine, 5-bromo-2,4-dimethyl-
- CBNumber
- CB12642830
- Molecular Formula
- C6H7BrN2
- Formula Weight
- 187.04
- MOL File
- 69696-37-3.mol
5-broMo-2,4-diMethyl-pyriMidine Property
- Melting point:
- 136-137 °C
- Boiling point:
- 78-81 °C(Press: 18 Torr)
- Density
- 1.500±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 0.96±0.29(Predicted)
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B623725
- Product name
- 5-Bromo-2,4-dimethylpyrimidine
- Packaging
- 50mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- HCH0366801
- Product name
- 5-BROMO-2,4-DIMETHYLPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.48
- Updated
- 2021/12/16
- Product number
- 2221AQ
- Product name
- 5-Bromo-2,4-dimethylpyrimidine
- Packaging
- 1g
- Price
- $1254.8
- Updated
- 2021/12/16
- Product number
- A111325
- Product name
- 5-Bromo-2,4-dimethylpyrimidine
- Purity
- 98%
- Packaging
- 100mg
- Price
- $86
- Updated
- 2021/12/16
- Product number
- A111325
- Product name
- 5-Bromo-2,4-dimethylpyrimidine
- Purity
- 98%
- Packaging
- 250mg
- Price
- $129
- Updated
- 2021/12/16
5-broMo-2,4-diMethyl-pyriMidine Chemical Properties,Usage,Production
Synthesis
69696-35-1
69696-37-3
c) Synthesis of 5-bromo-2,4-dimethylpyrimidine. A mixture of 5-bromo-4-chloro-2,6-dimethylpyrimidine (2.73 g, 12.33 mmol), 4-methylbenzenesulfonylhydrazine (4.19 mL, 37.0 mmol) and chloroform (40 mL) was heated and refluxed for 16 hr at 90 °C. Upon completion of the reaction, the mixture was cooled to room temperature, the solid product was collected by filtration and washed with chloroform. The resulting solid (4.75 g) was confirmed as the expected intermediate by LC-MS analysis. Subsequently, the intermediate was mixed with 0.94 M aqueous sodium carbonate solution (40 mL, 37.7 mmol) and heated and stirred at 90 °C for 1.5 hours. After the reaction mixture was cooled, it was extracted three times with ethyl acetate, the organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the title compound, 5-bromo-2,4-dimethylpyrimidine (1.17 g, 51% yield), as a tan oil, which was crystallized after standing. LC-MS (ES+) m/z: 187 [M + H]+.
References
[1] Synthesis, 1984, # 3, p. 252 - 254
[2] Patent: WO2013/96151, 2013, A1. Location in patent: Page/Page column 131
[3] Patent: US2016/176882, 2016, A1
[4] Patent: WO2017/221092, 2017, A1
[5] Patent: WO2017/221100, 2017, A1
5-broMo-2,4-diMethyl-pyriMidine Preparation Products And Raw materials
Raw materials
Preparation Products
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