ChemicalBook > CAS DataBase List > N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide

N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide

Product Name
N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide
CAS No.
1401031-52-4
Chemical Name
N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide
Synonyms
100859;LSN2463359;LSN2463359, 10 mM in DMSO;N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide;N-(1-Methylethyl)-5-(pridin-4-ylethynyl)pyridine-2-carboxamide;N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide;2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]-
CBNumber
CB12645129
Molecular Formula
C16H15N3O
Formula Weight
265.31
MOL File
1401031-52-4.mol
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N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Property

storage temp. 
2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
color 
white to light brown
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Safety

Hazard Codes 
Xi
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0721
Product name
LSN2463359
Purity
≥98% (HPLC)
Packaging
5mg
Price
$106
Updated
2022/05/15
Sigma-Aldrich
Product number
SML0721
Product name
LSN2463359
Purity
≥98% (HPLC)
Packaging
25mg
Price
$416
Updated
2022/05/15
Cayman Chemical
Product number
22104
Product name
LSN2463359
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
22104
Product name
LSN2463359
Purity
≥98%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
22104
Product name
LSN2463359
Purity
≥98%
Packaging
10mg
Price
$184
Updated
2024/03/01
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N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Chemical Properties,Usage,Production

Uses

LSN 2463359 is used as a positive and potent allosteric modulator of the mGlu5 receptor (1,2). LSN 2463359 is highly selective for mGlu5 and exhibits little to no activity for mGlu1-4, mGlu8 and GABAB receptors. Studies showed that LSN 2463359 promotes wakefulness in vivo and cognitive activity. LSN 2463359 also Improve memory and learning characteristics in mice.

storage

Store at +4°C

N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Suppliers

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1401031-52-4, N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMideRelated Search:

N-Methyl-4-((2-(Methylthio)benzo[d]thiazol-6-yl)oxy)picolinaMide

  • N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide
  • LSN2463359
  • N-(1-Methylethyl)-5-(pridin-4-ylethynyl)pyridine-2-carboxamide
  • N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide
  • 100859
  • 2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]-
  • LSN2463359, 10 mM in DMSO
  • 1401031-52-4