5-Ethoxypyrazine-2-carboxylic acid
- Product Name
- 5-Ethoxypyrazine-2-carboxylic acid
- CAS No.
- 1220330-11-9
- Chemical Name
- 5-Ethoxypyrazine-2-carboxylic acid
- Synonyms
- 5-Ethoxypyrazine-2-carboxylic acid;5-Eethoxypyrazine-2-carboxylic acid;2-Pyrazinecarboxylic acid, 5-ethoxy-
- CBNumber
- CB12666081
- Molecular Formula
- C7H8N2O3
- Formula Weight
- 168.15
- MOL File
- 1220330-11-9.mol
5-Ethoxypyrazine-2-carboxylic acid Property
- Boiling point:
- 306.1±37.0 °C(Predicted)
- Density
- 1.304±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.20±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- E938125
- Product name
- 5-Ethoxypyrazine-2-carboxylicAcid
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CHM0390713
- Product name
- 5-ETHOXYPYRAZINE-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.02
- Updated
- 2021/12/16
- Product number
- 4192AA
- Product name
- 5-Ethoxypyrazine-2-carboxylicacid
- Packaging
- 5g
- Price
- $860
- Updated
- 2021/12/16
- Product number
- A312272
- Product name
- 5-Ethoxypyrazine-2-carboxylicacid
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $48
- Updated
- 2021/12/16
- Product number
- A312272
- Product name
- 5-Ethoxypyrazine-2-carboxylicacid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $177
- Updated
- 2021/12/16
5-Ethoxypyrazine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
1262803-60-0
1220330-11-9
Step 2: (0533) To a solution of tetrahydrofuran (THF, 3 mL) of the compound from Step 1 (110 mg, 0.60 mmol) was added an aqueous solution of lithium hydroxide (LiOH) (2 M, 0.90 mL, 1.8 mmol). The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction solution was adjusted to pH 1 with 1 M hydrochloric acid (HCl, aq.) The aqueous layer was extracted with ethyl acetate (EtOAc, 3 × 3 mL). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give 5-ethoxypyrazine-2-carboxylic acid (75 mg, 74% yield).
References
[1] Patent: US2015/307465, 2015, A1. Location in patent: Paragraph 0533
[2] Patent: WO2011/9898, 2011, A1. Location in patent: Page/Page column 99
[3] Patent: US2012/190672, 2012, A1. Location in patent: Page/Page column 30
[4] Patent: WO2012/98213, 2012, A1. Location in patent: Page/Page column 61
5-Ethoxypyrazine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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