ChemicalBook > CAS DataBase List > 3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid

3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid

Product Name
3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid
CAS No.
1300690-48-5
Chemical Name
3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid
Synonyms
AP-24600;DA-12847;KB-310048;OZ477A282R;Ponatinib RC 7;UNII-OZ477A282R;3-(3-Imidazo[1,2-b]pyridazinylethynyl)-4-methylbenzoic Acid;3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid;3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-5-methylbenzoic acid;3-(2-LMIDAZO{1,2-B}PYRIDAZIN-3-YLETHYNY)-4-METHYLBENZOIC ACID
CBNumber
CB12666571
Molecular Formula
C16H11N3O2
Formula Weight
277.27744
MOL File
1300690-48-5.mol
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3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid Property

Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
4.05±0.10(Predicted)
form 
Solid
color 
Off-white to light yellow
CAS DataBase Reference
1300690-48-5
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
I706733
Product name
3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoicacid
Packaging
100mg
Price
$90
Updated
2021/12/16
Synthonix
Product number
I18504
Product name
3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoicacid
Purity
97.0%
Packaging
1g
Price
$310
Updated
2021/12/16
Activate Scientific
Product number
AS57459
Product name
3-(2-{Imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoic acid
Purity
95+%
Packaging
1g
Price
$347
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1052697
Product name
3-(2-(IMIDAZO[1,2-B]PYRIDAZIN-3-YL)ETHYNYL)-4-METHYLBENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$497.04
Updated
2021/12/16
Synthonix
Product number
I18504
Product name
3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoicacid
Purity
97.0%
Packaging
5g
Price
$940
Updated
2021/12/16
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3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid Chemical Properties,Usage,Production

Uses

AP24600 is an inactive metabolite of Ponatinib[1].

References

[1] Narayana I Narasimhan, et al. Evaluation of the effect of multiple doses of lansoprazole on the pharmacokinetics and safety of ponatinib in healthy subjects. Clin Drug Investig. 2014 Oct;34(10):723-9. DOI:10.1007/s40261-014-0225-y

3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid manufacturers

Career Henan Chemical Co
Product
3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid 1300690-48-5
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100g , 1kg, 5kg , 50kg
Release date
2020-01-07

1300690-48-5, 3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acidRelated Search:


  • 3-(3-Imidazo[1,2-b]pyridazinylethynyl)-4-methylbenzoic Acid
  • Benzoic acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-
  • 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid
  • AP-24600
  • 3-(2-iMidazo[1,2-b]pyridazin-3-ylethynyl)-4-Methyl-Benzoic acid
  • 3-(2-LMIDAZO{1,2-B}PYRIDAZIN-3-YLETHYNY)-4-METHYLBENZOIC ACID
  • Benzoic acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-me...
  • DA-12847
  • KB-310048
  • OZ477A282R
  • UNII-OZ477A282R
  • 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-5-methylbenzoic acid
  • Ponatinib RC 7
  • 3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoic acid - [I18504]
  • 1300690-48-5