ChemicalBook > CAS DataBase List > AVL 292 benzenesulfonate
AVL 292 benzenesulfonate
- Product Name
- AVL 292 benzenesulfonate
- CAS No.
- 1360053-81-1
- Chemical Name
- AVL 292 benzenesulfonate
- Synonyms
- CC-292 besylate);AVL-292 besylate;Spebrutinib besylate;AVL292 benzenesulfonate;AVL 292 benzenesulfonate;AVL-292 (benzenesulfonate);SPEBRUTINIB BESYLATE;CC-292 BESYLATE;Spebrutinib (AVL-292) benzenesulfonate;Spebrutinib besylate (AVL-292 benzenesulfonate;SPEBRUTINIB BESYLATE (AVL-292 BENZENESULFONATE; CC-292 BESYLATE)
- CBNumber
- CB12666591
- Molecular Formula
- C28H28FN5O6S
- Formula Weight
- 581.62
- MOL File
- 1360053-81-1.mol
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AVL 292 benzenesulfonate Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb611830
- Product name
- AVL-292 besylate
- Packaging
- 10mg
- Price
- $268.6
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611830
- Product name
- AVL-292 besylate
- Packaging
- 50mg
- Price
- $569.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611830
- Product name
- AVL-292 besylate
- Packaging
- 100mg
- Price
- $663
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31003749
- Product name
- AVL-292benzenesulfonate
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $67
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31003749
- Product name
- AVL-292benzenesulfonate
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $574
- Updated
- 2021/12/16
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AVL 292 benzenesulfonate Chemical Properties,Usage,Production
Uses
Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a potent inhibitor of Btk kinase activity (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s) in biochemical assays.
References
[1] Evans EK, et al. Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28. DOI:10.1124/jpet.113.203489
AVL 292 benzenesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
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