ChemicalBook > CAS DataBase List > AVL 292 benzenesulfonate

AVL 292 benzenesulfonate

Product Name
AVL 292 benzenesulfonate
CAS No.
1360053-81-1
Chemical Name
AVL 292 benzenesulfonate
Synonyms
CC-292 besylate);AVL-292 besylate;Spebrutinib besylate;AVL292 benzenesulfonate;AVL 292 benzenesulfonate;AVL-292 (benzenesulfonate);SPEBRUTINIB BESYLATE;CC-292 BESYLATE;Spebrutinib (AVL-292) benzenesulfonate;Spebrutinib besylate (AVL-292 benzenesulfonate;SPEBRUTINIB BESYLATE (AVL-292 BENZENESULFONATE; CC-292 BESYLATE)
CBNumber
CB12666591
Molecular Formula
C28H28FN5O6S
Formula Weight
581.62
MOL File
1360053-81-1.mol
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AVL 292 benzenesulfonate Property

storage temp. 
Store at -20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb611830
Product name
AVL-292 besylate
Packaging
10mg
Price
$268.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611830
Product name
AVL-292 besylate
Packaging
50mg
Price
$569.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611830
Product name
AVL-292 besylate
Packaging
100mg
Price
$663
Updated
2021/12/16
Crysdot
Product number
CD31003749
Product name
AVL-292benzenesulfonate
Purity
98+%
Packaging
5mg
Price
$67
Updated
2021/12/16
Crysdot
Product number
CD31003749
Product name
AVL-292benzenesulfonate
Purity
98+%
Packaging
100mg
Price
$574
Updated
2021/12/16
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AVL 292 benzenesulfonate Chemical Properties,Usage,Production

Uses

Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a potent inhibitor of Btk kinase activity (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s) in biochemical assays.

References

[1] Evans EK, et al. Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28. DOI:10.1124/jpet.113.203489

AVL 292 benzenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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AVL 292 benzenesulfonate Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9377
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58

1360053-81-1, AVL 292 benzenesulfonateRelated Search:


  • AVL 292 benzenesulfonate
  • AVL-292 (benzenesulfonate)
  • AVL292 benzenesulfonate
  • Spebrutinib (AVL-292) benzenesulfonate
  • AVL292 BENZENESULFONATE; AVL 292 BENZENESULFONATE; SPEBRUTINIB BESYLATE; CC-292 BESYLATE
  • AVL-292 besylate
  • CC-292 besylate)
  • Spebrutinib besylate (AVL-292 benzenesulfonate
  • SPEBRUTINIB BESYLATE (AVL-292 BENZENESULFONATE; CC-292 BESYLATE)
  • Spebrutinib besylate
  • SPEBRUTINIB BESYLATE;CC-292 BESYLATE
  • 1360053-81-1