ChemicalBook > CAS DataBase List > HOE-32020

HOE-32020

Product Name
HOE-32020
CAS No.
23554-99-6
Chemical Name
HOE-32020
Synonyms
HOE32020;HOE-32020;HOE 32020;2'-(4-Chlorophenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole;2,5'-Bi-1H-benzimidazole, 2'-(4-chlorophenyl)-5-(4-methyl-1-piperazinyl)- (9CI)
CBNumber
CB12666627
Molecular Formula
C25H23ClN6
Formula Weight
442.94
MOL File
23554-99-6.mol
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HOE-32020 Property

Boiling point:
715.6±70.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
25℃: DMSO or water Protect from light
form 
Powder
pka
10.68±0.10(Predicted)
color 
Light green to green
Appearance
Solid Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot
Product number
CD47000051
Product name
HOE32020
Purity
98+%
Packaging
50mg
Price
$168
Updated
2021/12/16
Crysdot
Product number
CD47000051
Product name
HOE32020
Purity
98+%
Packaging
100mg
Price
$224
Updated
2021/12/16
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HOE-32020 Chemical Properties,Usage,Production

Description

HOE 32020 is one of Hoechst stains which are Bis-benzimides used as blue fluorescent dyes to stain DNA.

Uses

HOE 32020 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].

References

[1] Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505. DOI:10.1177/23.7.1095650
[2] a b c "Hoechst Stains". Invitrogren (Molecular Probes).
[3] Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68. DOI:10.1016/0167-4781(88)90079-6

HOE-32020 Preparation Products And Raw materials

Raw materials

Preparation Products

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HOE-32020 Suppliers

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23554-99-6, HOE-32020Related Search:


  • HOE 32020
  • HOE32020
  • HOE-32020
  • 2,5'-Bi-1H-benzimidazole, 2'-(4-chlorophenyl)-5-(4-methyl-1-piperazinyl)- (9CI)
  • 2'-(4-Chlorophenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
  • 23554-99-6