Hoechst 33258 analog 3
- Product Name
- Hoechst 33258 analog 3
- CAS No.
- 23554-98-5
- Chemical Name
- Hoechst 33258 analog 3
- Synonyms
- Hoechst 33258 analog 3;Hoechst 33258 analog 3, BR;Hoechst 33258 analog 3,Inhibitor,inhibit;2,6'-Bibenzimidazole, 2'-(4-methylphenyl)-6-(4-methyl-1-piperazinyl)-;6-(4-Methylpiperazin-1-yl)-2'-(p-tolyl)-1H,3'H-2,5'-bibenzo[d]imidazole
- CBNumber
- CB12666632
- Molecular Formula
- C26H26N6
- Formula Weight
- 422.52
- MOL File
- 23554-98-5.mol
Hoechst 33258 analog 3 Property
- Boiling point:
- 703.1±70.0 °C | Condition: Press: 760 Torr
- Density
- 1.276±0.06 g/cm3
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- 25℃: DMSO or water Protect from light
- form
- Powder
- color
- Off-white to pink
- Appearance
- Light Yellow to Yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CD47000052
- Product name
- Hoechst33258analog3
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $168
- Updated
- 2021/12/16
- Product number
- CD47000052
- Product name
- Hoechst33258analog3
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $224
- Updated
- 2021/12/16
Hoechst 33258 analog 3 Chemical Properties,Usage,Production
Description
Hoechst 33258 analog 3 is a blue fluorescent dye used for staining DNA.
Uses
Hoechst 33258 analog 3 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
References
[1] Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68. DOI:10.1016/0167-4781(88)90079-6
[2] Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505. DOI:10.1177/23.7.1095650
[3] a b c "Hoechst Stains". Invitrogren (Molecular Probes).
Hoechst 33258 analog 3 Preparation Products And Raw materials
Raw materials
Preparation Products
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