ChemicalBook > CAS DataBase List > SJB3-019A
SJB3-019A
- Product Name
- SJB3-019A
- CAS No.
- 2070015-29-9
- Chemical Name
- SJB3-019A
- Synonyms
- SJB3-019A;SJB3-019A, 10 mM in DMSO;SJB-3-019A,SJB3 019A,SJB3019A;2-(Pyridin-3-yl)naphtho[2,3-d]oxazole-4,9-dione;Naphth[2,3-d]oxazole-4,9-dione, 2-(3-pyridinyl)-
- CBNumber
- CB12666687
- Molecular Formula
- C16H8N2O3
- Formula Weight
- 276.25
- MOL File
- 2070015-29-9.mol
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SJB3-019A Property
- Boiling point:
- 526.1±52.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 2.74±0.12(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ApexBio Technology
- Product number
- B1307
- Product name
- SJB3-019A
- Packaging
- 10mM(in 1mL DMSO)
- Price
- $210
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B1307
- Product name
- SJB3-019A
- Packaging
- 5mg
- Price
- $220
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-1649
- Product name
- SJB3-019A
- Purity
- >99.00%
- Packaging
- 5mg
- Price
- $286
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B1307
- Product name
- SJB3-019A
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-1649
- Product name
- SJB3-019A
- Purity
- >99.00%
- Packaging
- 10mg
- Price
- $432
- Updated
- 2021/12/16
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SJB3-019A Chemical Properties,Usage,Production
Uses
SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM.
Biological Activity
potent USP1 inhibitor th at induces ID1 degradation, upregulation of p21 and cytoxicity in K562 and other leukemic cell lines
References
[1] Helena Mistry, et al. Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther Published OnlineFirst October 15, 2013. DOI:10.1158/1535-7163.MCT-13-0103-T
SJB3-019A Preparation Products And Raw materials
Raw materials
Preparation Products
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SJB3-019A Suppliers
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