ChemicalBook > CAS DataBase List > 2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-

Product Name
2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-
CAS No.
779353-02-5
Chemical Name
2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-
Synonyms
CDK-IN-6;CDK IN 6,CDKIN6;2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-;(S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol
CBNumber
CB12667765
Molecular Formula
C21H28N6O
Formula Weight
380.48662
MOL File
779353-02-5.mol
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2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Property

Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (131.41 mM; Need ultrasonic)
pka
15.15±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chemenu
Product number
CM331253
Product name
(S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol
Purity
95%+
Packaging
100mg
Price
$864
Updated
2021/12/16
Chemenu
Product number
CM331253
Product name
(S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol
Purity
95%+
Packaging
250mg
Price
$1680
Updated
2021/12/16
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2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Chemical Properties,Usage,Production

Biological Activity

CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1]. Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1].

References

[1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1.

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Suppliers

China 5 Global 5
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
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61
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3427
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24017
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58
Nanjing Bic Biotechnology Co., Ltd
Tel
025-58906079
Email
sales@bicbiotech.com
Country
China
ProdList
6539
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Nanjing Bicbiotechnology Co., Ltd
Tel
+86-2552131256 +86-18251840740
Email
sales@bicbiotech.com
Country
China
ProdList
6000
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58

779353-02-5, 2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-Related Search:


  • 2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-
  • (S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol
  • CDK-IN-6
  • CDK IN 6,CDKIN6
  • 779353-02-5