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PLpro inhibitor

Product Name
PLpro inhibitor
CAS No.
1093070-14-4
Chemical Name
PLpro inhibitor
Synonyms
HY-17542;PLpro inhibitor;Plpro-IN-6(PLpro inhibitor);5-acetamido-2-methyl-n-(2-naphthalen-1-ylethyl)benzamide;5-acetamido-2-methyl-N-[2-(1-naphthalenyl)ethyl]benzamide;5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-;5-acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide;Inhibitor,SARS-CoV,SARS coronavirus,PLpro inhibitor,inhibit;5-Acetylamino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide;(R)-5-Acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide
CBNumber
CB12685934
Molecular Formula
C22H22N2O2
Formula Weight
346.42
MOL File
1093070-14-4.mol
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PLpro inhibitor Property

Boiling point:
584.7±50.0 °C(Predicted)
Density 
1.189±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml
form 
Powder
pka
14.13±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CCH0000210
Product name
5-ACETYLAMINO-2-METHYL-N-(1R-NAPHTHALEN-1-YL-ETHYL)-BENZAMIDE
Purity
95.00%
Packaging
10MG
Price
$866.25
Updated
2021/12/16
ChemScene
Product number
CS-2273
Product name
PLproinhibitor
Purity
99.79%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-2273
Product name
PLproinhibitor
Purity
99.79%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-2273
Product name
PLproinhibitor
Purity
99.79%
Packaging
50mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-2273
Product name
PLproinhibitor
Purity
99.79%
Packaging
100mg
Price
$2520
Updated
2021/12/16
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PLpro inhibitor Chemical Properties,Usage,Production

Definition

ChEBI: KOM70144 is a benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively). It has a role as a protease inhibitor and an anticoronaviral agent. It is a member of naphthalenes, a member of benzamides, a secondary carboxamide and a member of acetamides. It is functionally related to a GRL-0617.

storage

Store at -20°C

PLpro inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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PLpro inhibitor Suppliers

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1093070-14-4, PLpro inhibitorRelated Search:


  • PLpro inhibitor
  • 5-(Acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide
  • 5-Acetylamino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide
  • 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-
  • BENZAMIDE; 5-(ACETYLAMINO)-2-METHYL-N-[(1R)-1-(1-NAPHTHALENYL)ETHYL]-
  • 5-acetamido-2-methyl-N-[2-(1-naphthalenyl)ethyl]benzamide
  • 5-acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide
  • 5-acetamido-2-methyl-n-(2-naphthalen-1-ylethyl)benzamide
  • (R)-5-Acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide
  • Inhibitor,SARS-CoV,SARS coronavirus,PLpro inhibitor,inhibit
  • HY-17542
  • Plpro-IN-6(PLpro inhibitor)
  • 1093070-14-4