4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
- Product Name
- 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
- CAS No.
- 163622-50-2
- Chemical Name
- 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
- Synonyms
- 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine;5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-;5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
- CBNumber
- CB12704376
- Molecular Formula
- C6H5IN4
- Formula Weight
- 260.04
- MOL File
- 163622-50-2.mol
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Property
- Boiling point:
- 254.0±50.0 °C(Predicted)
- Density
- 2.58±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 11.57±0.20(Predicted)
- Appearance
- Off-white to light brown Solid
- InChI
- InChI=1S/C6H5IN4/c7-3-1-9-6-4(3)5(8)10-2-11-6/h1-2H,(H3,8,9,10,11)
- InChIKey
- KLKWCKQHBCUTCL-UHFFFAOYSA-N
- SMILES
- C1=NC(N)=C2C(I)=CNC2=N1
- CAS DataBase Reference
- 163622-50-2
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I1161
- Product name
- 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- Packaging
- 1G
- Price
- $83
- Updated
- 2025/07/31
- Product number
- I1161
- Product name
- 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- Packaging
- 5G
- Price
- $248
- Updated
- 2025/07/31
- Product number
- I737268
- Product name
- 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- AMTH139
- Product name
- 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- Packaging
- 10g
- Price
- $280
- Updated
- 2021/12/16
- Product number
- 3H30-H-05
- Product name
- 4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 1g
- Price
- $135
- Updated
- 2021/12/16
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Chemical Properties,Usage,Production
Synthesis
1500-85-2
163622-50-2
The general procedure for the synthesis of 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine using 4-amino-7H-pyrrolo[2,3-d]pyrimidine as starting material was as follows: 7H-pyrrolo[2,3-d]pyrimidin-4-amine (1.3 g, 9.7 mmol, 1.0 eq.) was dissolved in chloroform (45 mL) at room temperature, followed by the addition of N-iodo-substituted butylenedi imide (NIS, 2.18 g, 9.7 mmol, 1.0 equiv). The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, the precipitate was collected by filtration and dried under vacuum to afford the target product 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine (2.09 g, 83% yield) as a white solid.
References
[1] Patent: WO2018/11628, 2018, A1. Location in patent: Paragraph 00303
[2] Patent: CN106831790, 2017, A. Location in patent: Paragraph 0043-0046
[3] Patent: WO2014/184069, 2014, A1. Location in patent: Page/Page column 33; 34
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 28, p. 5158 - 5167
[5] Patent: WO2017/161344, 2017, A1. Location in patent: Paragraph 0813; 0820
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Suppliers
- Tel
- 0551-68136310 18705595789
- Fax
- 0551-68136307
- 939249921@qq.com
- Country
- China
- ProdList
- 46
- Advantage
- 55
- Tel
- 21-57721279 18121011378
- Fax
- QQ：14057904
- sales@shydchem.com.cn
- Country
- China
- ProdList
- 998
- Advantage
- 56
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 18986259541 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3744
- Advantage
- 58
- Tel
- 18993966060
- Fax
- 0943-8288977
- sales@techbiochem.com
- Country
- China
- ProdList
- 816
- Advantage
- 61
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9341
- Advantage
- 55
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 021-34979681; 17701870669
- Fax
- 021-34979681
- 41513101@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 18621295758; 18621295758
- Fax
- -QQ:1449085402
- 1449085402@qq.com
- Country
- China
- ProdList
- 1973
- Advantage
- 55
View Lastest Price from 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine manufacturers
- Product
- 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine 163622-50-2
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-08