ChemicalBook > CAS DataBase List > Sofosbuvir IMpurity
Sofosbuvir IMpurity
- Product Name
- Sofosbuvir IMpurity
- CAS No.
- 1520010-86-9
- Chemical Name
- Sofosbuvir IMpurity
- Synonyms
- Sofosbuvir IMpurity;Sofosbuvir Impurity 114;Sofosbuvir Phosphate Impurity;Sofosbuvir Phenoxyphosphinyl Impurity;SofosbuvirImpurity43CyclohexylamineSalt;L-Alanine, N-(hydroxyphenoxyphosphinyl)-, 1-methylethyl ester;(2S)-Isopropyl 2-((hydroxy(phenoxy)phosphoryl)amino)propanoate (Sofosbuvir Impurity)
- CBNumber
- CB12710427
- Molecular Formula
- C12H18NO5P
- Formula Weight
- 287.25
- MOL File
- 1520010-86-9.mol
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Sofosbuvir IMpurity Chemical Properties,Usage,Production
Uses
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Sofosbuvir IMpurity Preparation Products And Raw materials
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Preparation Products
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1520010-86-9, Sofosbuvir IMpurityRelated Search:
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((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
Sofosbuvir IMpurity C 1337482-15-1
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(R)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
Sofosbuvir Impurity 32
SofosBuvir Impurity 14
N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
sofosBuvir impurity 47
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester
(2R,3R,4R,5R)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-chloro-4-Methyltetrahydrofuran-3-yl benzoate
Sofosbuvir IMpurity 4
Sofosbuvir IMpurity B