Uses
ChemicalBook > CAS DataBase List > CID 16020046

CID 16020046

Uses
Product Name
CID 16020046
CAS No.
834903-43-4
Chemical Name
CID 16020046
Synonyms
CS-1189;C390-0219;CID 16020046;CID16020046 (CID 16020046);CID16020046;CID 16020046;CID 16020046;4-(4-(3-Hydroxyphenyl)-6-oxo-3-(p-tolyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)benzoic acid;4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid;4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid;Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-;CID 16020046,cells,CID16020046,wound,Ca2+,inhibit,ERK1/2,GPR55,hERG,acetylcholinesterase,HEK,CID-16020046,function,phosphorylation,KCNH2,LPI,healing,endothelial,platelet,Inhibitor,HMVEC,lysophosphatidylinositol,m-opioid,G protein-coupled receptor 55
CBNumber
CB12715619
Molecular Formula
C25H19N3O4
Formula Weight
425.44
MOL File
834903-43-4.mol
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CID 16020046 Property

Boiling point:
748.1±60.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble1mg/mL, clear (warmed)
pka
4.27±0.10(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0805
Product name
CID16020046
Purity
≥98% (HPLC)
Packaging
5mg
Price
$151
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0805
Product name
CID16020046
Purity
≥98% (HPLC)
Packaging
25mg
Price
$537
Updated
2024/03/01
Cayman Chemical
Product number
15247
Product name
CID16020046
Purity
≥98%
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
15247
Product name
CID16020046
Purity
≥98%
Packaging
5mg
Price
$112
Updated
2024/03/01
Cayman Chemical
Product number
15247
Product name
CID16020046
Purity
≥98%
Packaging
10mg
Price
$172
Updated
2024/03/01
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CID 16020046 Chemical Properties,Usage,Production

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Biochem/physiol Actions

CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells.

storage

Store at +4°C

CID 16020046 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID 16020046 Suppliers

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834903-43-4, CID 16020046Related Search:


  • 4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid
  • CID16020046 (CID 16020046)
  • Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-
  • CID 16020046
  • 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid
  • CS-1189
  • CID16020046;CID 16020046;CID 16020046
  • C390-0219
  • 4-(4-(3-Hydroxyphenyl)-6-oxo-3-(p-tolyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)benzoic acid
  • CID 16020046,cells,CID16020046,wound,Ca2+,inhibit,ERK1/2,GPR55,hERG,acetylcholinesterase,HEK,CID-16020046,function,phosphorylation,KCNH2,LPI,healing,endothelial,platelet,Inhibitor,HMVEC,lysophosphatidylinositol,m-opioid,G protein-coupled receptor 55
  • 834903-43-4