KRCA-0008

Product Name: KRCA-0008
CAS No.: 1472795-20-2
Chemical Name: KRCA-0008
Synonyms: GABANG;GABA-NG;GABA NG;CS-1715;KRCA-008;KRCA-0008;Pikamilone Na;KRCA 0008|||KRCA0008;KRCA-0008 >=98% (HPLC);KRCA-0008, 10 mM in DMSO
CBNumber: CB12715644
Molecular Formula: C30H37ClN8O4
Formula Weight: 609.12
MOL File: 1472795-20-2.mol

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KRCA-0008 Property

Boiling point:: 870.2±75.0 °C(Predicted)
Density: 1.332±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: H2O : < 0.1 mg/mL (insoluble)
form: Powder
pka: 3.99±0.50(Predicted)
color: White to gray

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Tocris

Product number: 5098
Product name: KRCA0008
Purity: ≥99%(HPLC)
Packaging: 10
Price: $127
Updated: 2021/12/16

Tocris

Product number: 5098
Product name: KRCA0008
Purity: ≥99%(HPLC)
Packaging: 50
Price: $538
Updated: 2021/12/16

TRC

Product number: K660323
Product name: KRCA0008
Packaging: 1mg
Price: $110
Updated: 2021/12/16

Usbiological

Product number: 255608
Product name: KRCA 0008
Packaging: 10mg
Price: $502
Updated: 2021/12/16

ChemScene

Product number: CS-3341
Product name: KRCA-0008
Packaging: 5mg
Price: $50
Updated: 2021/12/16

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KRCA-0008 Chemical Properties,Usage,Production

Uses

KRCA 0008 is a potent and selective ALK inhibitors for anticancer treatment.

in vivo

KRCA-0008 (25 and 50 mg/kg; p.o. twice a day for two weeks) suppresses tumor growth in an ALK-positive Karpas-299 xenograft model^[2].

Animal Model:	NOD/SCID mice with Karpas-299 xenografts^[2]
Dosage:	25 and 50 mg/kg
Administration:	Oral gavage; 25 and 50 mg/kg twice a day; for two weeks
Result:	Significantly inhibited tumor growth by inhibiting NPM-ALK phosphorylation without showing overt signs of toxicity or significant compound-related body weight loss.

storage

Store at -20°C

KRCA-0008 Preparation Products And Raw materials

Raw materials

Preparation Products

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KRCA-0008 Suppliers

China 83 India 1 United Kingdom 2 United States 11 Global 97

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070 13913916777
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16057
Advantage: 64

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 18930833303 18930833303
Fax: +86 (21) 2024-2659
Email: sales@changyanchem.cn
Country: China
ProdList: 5001
Advantage: 55

1472795-20-2, KRCA-0008Related Search:

CS-1715

KRCA-0008

KRCA-008

1,1'-[(5-Chloro-2,4-pyrimidinediyl)bis[imino(3-methoxy-4,1-phenylene)-4,1-piperazinediyl]]bisethanone

Ethanone, 1,1'-[(5-chloro-2,4-pyrimidinediyl)bis[imino(3-methoxy-4,1-phenylene)-4,1-piperazinediyl]]bis-

KRCA-0008 >=98% (HPLC)

GABA NG

GABANG

GABA-NG

Pikamilone Na

1,1'-(4,4'-(((5-chloropyrimidine-2,4-diyl)bis(azanediyl))bis(3-methoxy-4,1-phenylene))bis(piperazine-4,1-diyl))diethanone

1,1'-((((5-Chloropyrimidine-2,4-diyl)bis(azanediyl))bis(3-methoxy-4,1-phenylene))bis(piperazine-4,1-diyl))bis(ethan-1-one)

KRCA 0008|||KRCA0008

1-(4-{4-[(4-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-chloropyrimidin-2-yl)amino]-3-methoxyphenyl}piperazin-1-yl)ethan-1-one

KRCA-0008, 10 mM in DMSO

1472795-20-2

C30H37ClN8O4

Inhibitors