(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Product Name: (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
CAS No.: 475473-26-8
Chemical Name: (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
Synonyms: CORM-3;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium;Tricarbonylchloro(glycinato)ruthenium (II);(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
CBNumber: CB12717709
Molecular Formula: C5H3ClNO5Ru
Formula Weight: 293.6
MOL File: 475473-26-8.mol

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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Property

storage temp.: -20°C
solubility: H2O: soluble20mg/mL, clear
form: powder
color: light yellow to dark yellow
Water Solubility: Soluble to 100 mM in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0496
Product name: CORM-3
Packaging: 10mg
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0496
Product name: CORM-3
Packaging: 50mg
Price: $496
Updated: 2024/03/01

Tocris

Product number: 5320
Product name: CORM3
Packaging: 50
Price: $357
Updated: 2021/12/16

Usbiological

Product number: 255030
Product name: CORM 3
Packaging: 10mg
Price: $333
Updated: 2021/12/16

TRC

Product number: C724813
Product name: CORM3
Packaging: 25mg
Price: $695
Updated: 2021/12/16

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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemical Properties,Usage,Production

Uses

CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H₂O₂-induced apoptosis using primary rabbit lens epithelial cells.

Biochem/physiol Actions

CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.

storage

Store at -20°C

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Preparation Products And Raw materials

Raw materials

Preparation Products

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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Suppliers

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475473-26-8, (OC-6-44)-Tricarbonylchloro(glycinato)rutheniumRelated Search:

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

CORM-3

Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-

Carbon monoxide releasing molecule 3

Tricarbonylchloro(glycinato)ruthenium (II)

Tricarbonylchloro(glycinato)ruthenium

inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)

(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium

475473-26-8

C5H4ClNO5Ru

Inhibitors