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DFSX-2

Product Name
DFSX-2
CAS No.
442526-91-2
Chemical Name
DFSX-2
Synonyms
Delafloxcain;DFSX-2;CB12718322;Delafloxacin impurities6;Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester;3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester
CBNumber
CB12718322
Molecular Formula
C24H23F3N4O5
Formula Weight
504.46
MOL File
442526-91-2.mol
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DFSX-2 Property

Melting point:
201-209 °C(Solv: water (7732-18-5))
Boiling point:
652.5±55.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20 °C
solubility 
DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml
pka
0.92±0.10(Predicted)
Appearance
Off-White Solid
InChIKey
VMXLACIKUJJQTC-UHFFFAOYSA-N
SMILES
N1(C2=NC(N)=C(F)C=C2F)C2=C(C=C(F)C(N3CC(OC(=O)C(C)C)C3)=C2)C(=O)C(C(OCC)=O)=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot
Product number
CD11123018
Product name
Ethyl1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Purity
95+%
Packaging
250mg
Price
$295
Updated
2021/12/16
Alichem
Product number
442526912
Product name
Ethyl1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Packaging
250mg
Price
$407.88
Updated
2021/12/16
Crysdot
Product number
CD11123018
Product name
Ethyl1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Purity
95+%
Packaging
1g
Price
$735
Updated
2021/12/16
Chemenu
Product number
CM222957
Product name
Ethyl1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Purity
95%
Packaging
1g
Price
$926
Updated
2021/12/16
Alichem
Product number
442526912
Product name
Ethyl1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Packaging
1g
Price
$970.2
Updated
2021/12/16
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DFSX-2 Chemical Properties,Usage,Production

Description

DFSX-2 is a precursor in the synthesis of the fluoroquinolone antibiotic ABT-492 (delafloxacin; Item Nos. 20314 | 27935).1WARNING This product is not for human or veterinary use.

References

[1] ANTHONY R. HAIGHT. Synthesis of the Quinolone ABT-492: Crystallizations for Optimal Processing[J]. Organic Process Research & Development, 2006, 10 4: 751-756. DOI: 10.1021/op060054e

DFSX-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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DFSX-2 Suppliers

Elucigen bio
Tel
13501719342; 13501719342
Email
wayne.zheng@elucigenbio.com
Country
China
ProdList
5000
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9411
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15724
Advantage
64
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Shanghai Mixiu Chemical Co., Ltd.
Tel
18101936766
Fax
021-58583907
Email
eileen@shmychem.com
Country
China
ProdList
350
Advantage
55
Guangzhou BestWay Pharmaceutical Technology Co., Ltd.
Tel
+86-20-13924213170
Fax
020-28069313
Email
baimei141202@163.com
Country
China
ProdList
8
Advantage
55
Twochem Co.Ltd
Tel
021-021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
304
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3946
Advantage
58
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View Lastest Price from DFSX-2 manufacturers

Jinan Jianfeng Chemical Co., Ltd
Product
DFSX-2;Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate 442526-91-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
6000kg
Release date
2022-09-21
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Dfsx-2 442526-91-2
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-11-06
Career Henan Chemical Co
Product
DFSX-2 442526-91-2
Price
US $8.00/KG
Min. Order
1KG
Purity
>98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

442526-91-2, DFSX-2Related Search:


  • DFSX-2
  • Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isobutyryloxy)azetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
  • Delafloxcain
  • 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester
  • 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester
  • Delafloxacin impurities6
  • CB12718322
  • 442526-91-2
  • C24H23F3N4O5