3-ethynylpyridin-2-aMine

Product Name: 3-ethynylpyridin-2-aMine
CAS No.: 67346-74-1
Chemical Name: 3-ethynylpyridin-2-aMine
Synonyms: 110892;3-ethynylpyridin-2-aMine;3-Ethynyl-2-pyridinamine;2-Amino-3-ethynylpyridine;2-Pyridinamine, 3-ethynyl-;3-Ethynylpyridin-2-amine - [E45198]
CBNumber: CB12718342
Molecular Formula: C7H6N2
Formula Weight: 118.14
MOL File: 67346-74-1.mol

More

Less

3-ethynylpyridin-2-aMine Property

Melting point:: 86-87 °C(Solv: ligroine (8032-32-4))
Boiling point:: 246.6±25.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 5.08±0.36(Predicted)
Appearance: Brown to dark brown Solid

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: B126125
Product name: 3-ethynylpyridin-2-amine
Packaging: 50mg
Price: $110
Updated: 2021/12/16

TRC

Product number: B126125
Product name: 3-ethynylpyridin-2-amine
Packaging: 100mg
Price: $175
Updated: 2021/12/16

Synthonix

Product number: E45198
Product name: 3-Ethynylpyridin-2-amine
Purity: 97%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

Synthonix

Product number: E45198
Product name: 3-Ethynylpyridin-2-amine
Purity: 97%
Packaging: 250mg
Price: $140
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: E15112
Product name: 3-Ethynylpyridin-2-amine
Purity: 98%
Packaging: 250mg
Price: $150
Updated: 2021/12/16

More

Less

3-ethynylpyridin-2-aMine Chemical Properties,Usage,Production

Synthesis

936342-23-3

67346-74-1

GENERAL STEPS: Preparation of 3-ethynylpyridin-2-amine; Tetrabutylammonium fluoride (1 M tetrahydrofuran solution, 20 mL, 20 mmol) was added to a tetrahydrofuran (300 mL) solution of 3-((trimethylsilyl)ethynyl)pyridin-2-amine (28.1 g, 148 mmol), and the reaction was stirred at room temperature for 15 minutes. Upon completion of the reaction, water was added to the reaction solution and then extracted four times with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: heptane/ethyl acetate = 1:1, subsequently adjusted to 1:2) to afford the target product 3-ethynylpyridin-2-amine (16.4 g, 93.7% yield).1H-NMR (DMSO-d6) δ (ppm): 4.43 (1H, s), 6.14 (2H, brs), 6.53 (1H, dd, J =4.8 Hz, 7.2 Hz), 7.53 (1H, d, J=7.2 Hz), 7.96 (1H, d, J=4.8 Hz).

References

[1] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 51-52
[2] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 53-54
[3] Patent: US2010/331282, 2010, A1. Location in patent: Page/Page column 11
[4] Chemistry - A European Journal, 2010, vol. 16, # 27, p. 7992 - 7995
[5] Patent: EP2065377, 2009, A1. Location in patent: Page/Page column 59

3-ethynylpyridin-2-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-ethynylpyridin-2-aMine Suppliers

China 27 India 2 United States 5 Global 34

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 88915
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19066
Advantage: 58

Aikon International Limited

Tel: 025-58859352 19370895928
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15082
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9965
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 6673
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 021-4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52678
Advantage: 58

Shanghai Union Medical Technology Co. Ltd.

Tel: 13120563767
Fax: 15669989863
Email: chemchen925@outlook.com
Country: China
ProdList: 611
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30227
Advantage: 58

Neostar United (Changzhou) Industrial Co., Ltd.

Tel: +86-0519-85551759 +8613506123987
Fax: +0086-519-85557389
Email: marketing1@neostarunited.com
Country: China
ProdList: 8828
Advantage: 58

67346-74-1, 3-ethynylpyridin-2-aMineRelated Search:

3-ethynylpyridin-2-aMine

110892

2-Amino-3-ethynylpyridine

2-Pyridinamine, 3-ethynyl-

3-Ethynyl-2-pyridinamine

3-Ethynylpyridin-2-amine - [E45198]

67346-74-1