1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)
- Product Name
- 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)
- CAS No.
- 799279-67-7
- Chemical Name
- 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)
- Synonyms
- C18 LPA;1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt);1-O-OCTADECYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE (AMMONIUM SALT);C18 LPA
- CBNumber
- CB12720763
- Molecular Formula
- C21H48NO6P
- Formula Weight
- 441.59
- MOL File
- 799279-67-7.mol
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Property
- storage temp.
- -20°C
- form
- powder
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Chemical Properties,Usage,Production
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
General Description
Lysophosphatidic?acid (LPA) is a class of phospholipids, which is water-soluble. It has a glycerol backbone attached?via?a phosphate group, an aliphatic chain and a hydroxyl group.?The aliphatic chain is linked to either?sn-1 or?sn-2 position and the phosphate group is connected to the?sn-3 position. The hydroxyl group is linked to the remaining?sn-1 or?sn-2?position.
Biochem/physiol Actions
Lysophosphatidic?acid (LPA) is a signaling molecule and alters various cellular responses through G protein-coupled receptors (GPCRs). It stimulates smooth muscle contraction, cytoskeleton rearrangement and chemotaxis. LPA is also involved in inducing neurotransmitter release, cell proliferation, platelet aggregation and Ca2+ mobilization. Increased levels of LPA in human plasma leads to ovarian cancer and atherosclerosis. LPA acts as a potential biomarker for ovarian cancer.
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
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