ChemicalBook > CAS DataBase List > 6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- Product Name
- 6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- CAS No.
- 1256577-71-5
- Chemical Name
- 6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- Synonyms
- CH5424802 analog;CH5424802 analog, 10 mM in DMSO;CH5424802 analog,CH-5424802 analog;6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile;5H-Benzo[b]carbazole-3-carbonitrile, 6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-
- CBNumber
- CB12721124
- Molecular Formula
- C28H30N4O2
- Formula Weight
- 454.56
- MOL File
- 1256577-71-5.mol
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N-Bromosuccinimide Price
Alichem
- Product number
- 1256577715
- Product name
- 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- Packaging
- 250mg
- Price
- $510.4
- Updated
- 2021/12/16
Alichem
- Product number
- 1256577715
- Product name
- 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- Packaging
- 1g
- Price
- $979.65
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11314363
- Product name
- 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1152
- Updated
- 2021/12/16
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6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Chemical Properties,Usage,Production
Uses
Alectinib analog (CH5424802 analog) is a selective ALK inhibitor with activity in blocking resistance gating mutations. The synthetic optimization of alectinib analog allows it to be combined with specific peptides to improve the ability to target cancer cells. Alectinib analog exhibits low micromolar IC50 values in antiproliferation and shows good cytotoxic effects. The inhibitory activity of alectinib analog is closely related to its stability and release of active ingredients. Alectinib analog demonstrated the ability to inhibit vascular septal length or width in an in vivo zebrafish model[1].
References
[1] Synthesis and Anti-Angiogenic Activity of Novel c(RGDyK) Peptide-Based JH-VII-139-1 Conjugates DOI:10.3390/pharmaceutics15020381
6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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