2-BroMo-3,6-difluoropyridine
- Product Name
- 2-BroMo-3,6-difluoropyridine
- CAS No.
- 1382786-22-2
- Chemical Name
- 2-BroMo-3,6-difluoropyridine
- Synonyms
- 2-BroMo-3,6-difluoropyridine;Pyridine, 2-bromo-3,6-difluoro-;2-bromo-3,6-difluoropyridine - [B71672]
- CBNumber
- CB12735857
- Molecular Formula
- C5H2BrF2N
- Formula Weight
- 193.98
- MOL File
- 1382786-22-2.mol
2-BroMo-3,6-difluoropyridine Property
- Boiling point:
- 182.7±35.0 °C(Predicted)
- Density
- 1.808±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -7.29±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3H32-B-4B
- Product name
- 2-Bromo-3,6-difluoropyridine
- Purity
- 95%
- Packaging
- 100mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- PC911877
- Product name
- 2-Bromo-3,6-difluoropyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $406
- Updated
- 2021/12/16
- Product number
- PC911877
- Product name
- 2-Bromo-3,6-difluoropyridine
- Purity
- 95%
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 3H32-B-4B
- Product name
- 2-Bromo-3,6-difluoropyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- PC911877
- Product name
- 2-Bromo-3,6-difluoropyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $988
- Updated
- 2021/12/16
2-BroMo-3,6-difluoropyridine Chemical Properties,Usage,Production
Synthesis
960371-07-7
1382786-22-2
Bromine (0.30 mL, 6 mmol) was slowly added dropwise to a stirring solution of (3,6-difluoropyridin-2-yl)hydrazine (435 mg, 3 mmol) in trichloromethane (6 mL) at room temperature. The reaction mixture was stirred at 60°C for 1 hour. Upon completion of the reaction, the mixture was cooled to 0°C and saturated sodium bicarbonate solution was added slowly and dropwise. Subsequently, dichloromethane was added for extraction, and the organic layer was separated, dried over anhydrous magnesium sulfate, filtered, and the solvent was removed by vacuum evaporation to afford 2-bromo-3,6-difluoropyridine (600 mg, 88% yield), the product being a dark colored oil.
References
[1] Patent: WO2012/83224, 2012, A1. Location in patent: Page/Page column 284-285
[2] Patent: US2018/170909, 2018, A1. Location in patent: Paragraph 2051; 2052
[3] Patent: US2015/18328, 2015, A1. Location in patent: Paragraph 1097; 1528
[4] Patent: WO2015/3640, 2015, A1. Location in patent: Page/Page column 241; 242; 329; 330
2-BroMo-3,6-difluoropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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