Hydroxytanshinone IIA

Product Name: Hydroxytanshinone IIA
CAS No.: 18887-18-8
Chemical Name: Hydroxytanshinone IIA
Synonyms: Hydroxytanshinone ⅡA;Hydroxytanshinone IIA;Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-9-hydroxy-1,6,6-trimethyl-
CBNumber: CB12743205
Molecular Formula: C19H18O4
Formula Weight: 310.34
MOL File: 18887-18-8.mol

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Hydroxytanshinone IIA Property

Boiling point:: 523.6±50.0 °C(Predicted)
Density: 1.291±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 14.17±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Arctom

Product number: CFN90353
Product name: HydroxytanshinoneIIA
Packaging: 5mg
Price: $568
Updated: 2021/12/16

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Hydroxytanshinone IIA Chemical Properties,Usage,Production

Description

Hydroxytanshinone ⅡA has good antiproliferative effect on SGC-7901,HeLa, and HepG 2 cell, the values of IC50 are 4.18, 6.08 and10.20 uM, respectively; it has tumor cell proliferation inhibition significantly stronger than the tanshinoneⅡA .

Uses

Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].

Definition

ChEBI: Hydroxytanshinone is an abietane diterpenoid.

References

[1] Peng Li, et al. Simultaneous determination of tanshinone IIA and its three hydroxylated metabolites by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(5):815-22. DOI:10.1002/rcm.2367

Hydroxytanshinone IIA Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxytanshinone IIA Suppliers

China 35 United States 2 Global 37

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18887-18-8, Hydroxytanshinone IIARelated Search:

TANSHINONE ⅡA Tanshinone IIA

Hydroxytanshinone IIA

Hydroxytanshinone ⅡA

Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-9-hydroxy-1,6,6-trimethyl-

18887-18-8