ChemicalBook > CAS DataBase List > N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride

Product Name
N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride
CAS No.
189061-11-8
Chemical Name
N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride
Synonyms
N-(4-(4-(2,3-DICHLOROPHENYL)PIPERAZIN-1-YL)BUTYL)-9H-FLUORENE-2-CARBOXAMIDE HCL;9H-Fluorene-2-carboxamide,N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-, monohydrochloride
CBNumber
CB12750474
Molecular Formula
C28H30Cl3N3O
Formula Weight
530.9163
MOL File
189061-11-8.mol
More
Less

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride Property

storage temp. 
2-8°C
solubility 
DMSO: ≥25mg/mL
form 
powder
color 
white to tan
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0066
Product name
NGB 2904 hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$133
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0066
Product name
NGB 2904 hydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$514
Updated
2025/07/31
Cayman Chemical
Product number
21457
Product name
NGB 2904 (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
21457
Product name
NGB 2904 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
21457
Product name
NGB 2904 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$210
Updated
2024/03/01
More
Less

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride Chemical Properties,Usage,Production

Uses

NGB 2904 Hydrochloride is a dopamine D3 receptor antagonist that inhibits cocaine’s rewarding effects and cocaine-induced reinstatement of drug seeking behavior in rats.

Biological Activity

Inhibition of dopamine D3 receptor function by NGB 2904 increases spontaneous locomotor activity in rodents.', 'NGB 2904 is a potent and selective dopamine D3 receptor antagonist with a D3/D2 ratio of 800 for r at and high binding affinity (1.4 nM) at the hD3 receptor with 150-fold selectivity for primate D3 receptors over primate D2L receptors. It attenuates the rewarding effects of cocaine and methamphetamine.

in vivo

NGB 2904 (26 μg/kg; a single s.c.) enhances amphetamine (26 mg/kg)-stimulated locomotion in wild-type mice[3].
NGB 2904 (0.026 μg-1 mg/kg; a single s.c. or once daily for 7 d) stimulates spontaneous locomotion in wild-type mice[3].

IC 50

D3 Receptor: 1.4 (Ki)

storage

Desiccate at +4°C

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride Suppliers

China 16 India 1 United Kingdom 1 United States 6 USA 1 Global 25
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9158
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32436
Advantage
58
Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
1010
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58

189061-11-8, N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochlorideRelated Search:


  • N-(4-(4-(2,3-DICHLOROPHENYL)PIPERAZIN-1-YL)BUTYL)-9H-FLUORENE-2-CARBOXAMIDE HCL
  • 9H-Fluorene-2-carboxamide,N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-, monohydrochloride
  • 189061-11-8