ChemicalBook > CAS DataBase List > 6-NITROIMIDAZO[1,2-A]PYRIDINE

6-NITROIMIDAZO[1,2-A]PYRIDINE

Product Name
6-NITROIMIDAZO[1,2-A]PYRIDINE
CAS No.
25045-82-3
Chemical Name
6-NITROIMIDAZO[1,2-A]PYRIDINE
Synonyms
6-NITROIMIDAZO[1,2-A]PYRIDINE;6-nitrosoimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 6-nitro-
CBNumber
CB1278345
Molecular Formula
C7H5N3O2
Formula Weight
163.13
MOL File
25045-82-3.mol
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6-NITROIMIDAZO[1,2-A]PYRIDINE Property

Melting point:
229-231°
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.70±0.50(Predicted)
Appearance
Yellow to brown Solid
InChI
InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-8-3-4-9(7)5-6/h1-5H
InChIKey
RXZZQEFTZIHXRI-UHFFFAOYSA-N
SMILES
C12=NC=CN1C=C([N+]([O-])=O)C=C2
CAS DataBase Reference
25045-82-3
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Safety

HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
045755
Product name
6-Nitroimidazo[1,2-a]pyridine
Purity
95+%
Packaging
1g
Price
$15
Updated
2021/12/16
Matrix Scientific
Product number
045755
Product name
6-Nitroimidazo[1,2-a]pyridine
Purity
95+%
Packaging
5g
Price
$60
Updated
2021/12/16
AK Scientific
Product number
Z4497
Product name
6-Nitroimidazo[1,2-a]pyridine
Packaging
1g
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
045755
Product name
6-Nitroimidazo[1,2-a]pyridine
Purity
95+%
Packaging
25g
Price
$150
Updated
2021/12/16
BroadPharm
Product number
BP-20256
Product name
6-nitro-imidazo[1,2-a]pyridine
Purity
96%
Packaging
5G
Price
$290
Updated
2021/12/16
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6-NITROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production

Synthesis

4214-76-0

2032-35-1

25045-82-3

In a 250 mL single-neck flask, bromoacetaldehyde diethyl acetal (42.5 g, 215.7 mmol) was dissolved in a mixture of 1 mol/L hydrochloric acid (120 mL) and ethanol (20 mL) and stirred at room temperature for 30 minutes. It was then heated to reflux and stirred continuously until the solution became clear. Upon completion of the reaction, the solution was cooled to room temperature and the pH was adjusted to near neutral with sodium bicarbonate solution. 2-Amino-5-nitropyridine (15.0 g, 107.8 mmol) was added and the reaction was stirred overnight at room temperature. At the end of the reaction, extraction was carried out with ethyl acetate (100 mL×3), the organic phases were combined, and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether:ethyl acetate = 2:1) to afford 13.7 g of yellow-brown crystalline 6-nitroimidazo[1,2-a]pyridine in 77.6% yield.

References

[1] Patent: CN107129496, 2017, A. Location in patent: Paragraph 0026-0028; 0014-0016; 0020-0022

6-NITROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-NITROIMIDAZO[1,2-A]PYRIDINE Suppliers

China 76 Germany 1 India 1 The Netherlands 1 United Kingdom 3 United States 14 Global 96
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
96815
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
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China
ProdList
35896
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56
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
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42934
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Shanghai Ennopharm Co., Ltd.
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+86 (21) 6435-5022
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China
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Sphinx Scientific Laboratory (Tianjin) Co., Ltd.
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022-66211289-843 13672102692
Fax
QQ：2377893365
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contact@sphinxpharm.com
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China
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361
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Acorn PharmaTech Co., Ltd.
Tel
025-58395930
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025-5861-9182
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sales@acornpharma.com
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China
ProdList
982
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60
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
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58
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
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View Lastest Price from 6-NITROIMIDAZO[1,2-A]PYRIDINE manufacturers

Career Henan Chemical Co
Product
6-NITROIMIDAZO[1,2-A]PYRIDINE 25045-82-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-25

25045-82-3, 6-NITROIMIDAZO[1,2-A]PYRIDINERelated Search:

6-NITROIMIDAZO[1,2-A]PYRIDINE 2-(CHLOROMETHYL)-6-NITRO-IMIDAZO[1,2-A]PYRIDINE 2-METHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 6-nitro-2-phenylimidazo[1,2-a]pyridine 2-(4-BROMOPHENYL)-6-NITROIMIDAZO[1,2-A]PYRIDINE 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 2-Methyl-6-nitroimidazo[1,2-a]pyridine 6-NITRO-3-PHENYL-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 1-(6-NITRO-2-THIOPHEN-2-YL-IMIDAZO[1,2-A]PYRIDIN-3-YLMETHYL)-PIPERIDINE-4-CARBOXYLIC ACID 2-(4-FLUOROPHENYL)-6-NITROIMIDAZO[1,2-A]PYRIDINE 1-(2-FURAN-2-YL-6-NITRO-IMIDAZO[1,2-A]PYRIDIN-3-YLMETHYL)-PIPERIDINE-4-CARBOXYLIC ACID 3-IODO-6-NITRO-IMIDAZO[1,2-A]PYRIDINE [4-(2-METHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDIN-3-YL)-THIAZOL-2-YL]-HYDRAZINE 2-FURAN-2-YL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE 2-BENZO[1,3]DIOXOL-5-YL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE 2-BENZO[1,3]DIOXOL-5-YL-3-BROMO-6-NITRO-IMIDAZO[1,2-A]PYRIDINE [4-(2,7-DIMETHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDIN-3-YL)-THIAZOL-2-YL]-HYDRAZINE (6-NITROIMIDAZO[1,2-A]PYRIDIN-8-YL)(PHENYL)METHANONE

  • 6-NITROIMIDAZO[1,2-A]PYRIDINE
  • IMidazo[1,2-a]pyridine, 6-nitro-
  • 6-nitrosoimidazo[1,2-a]pyridine
  • 25045-82-3