ChemicalBook > CAS DataBase List > PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE

PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE

Product Name
PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE
CAS No.
183449-57-2
Chemical Name
PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE
Synonyms
AβPE3-42;(Pyr3)-β-Amyloid(3-42);(Pyr3)-Amyloid β-Protein;(GLP3) BETA-AMYLOID (3-42);[PYR3]-BETA-AMYLOID (3-42);Pyr3] β- Amyloid (3-42), human;(Pyr3)-AMyloid b-Protein (3-42);(PYR3)-AMYLOID BETA-PROTEIN (3-42);[Pyr3]-Beta-Amyloid-Protein (3-42);pGlu3]-Amyloid β-Protein Fragment 3-42
CBNumber
CB1280443
Molecular Formula
C196H299N53O55S1
Formula Weight
4309.9
MOL File
183449-57-2.mol
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PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE Property

storage temp. 
−20°C
form 
solid
Sequence
{Pyr}-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0000227
Product name
[PYR3] - BETA- AMYLOID (3 - 42)
Purity
95.00%
Packaging
0.1MG
Price
$617.93
Updated
2021/12/16
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PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE Chemical Properties,Usage,Production

Uses

(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits[1].

References

[1] Takahashi-Ito K, et.al. Memantine inhibits β-amyloid aggregation and disassembles preformed β-amyloid aggregates. Biochem Biophys Res Commun. 2017 Nov 4;493(1):158-163. DOI:10.1016/j.bbrc.2017.09.058

PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE Suppliers

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183449-57-2, PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATERelated Search:

PYR-GLY-ARG-PNA PYR-MET-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-VAL-LEU-THR-NH2 FMRF-LIKE PEPTIDE MBP 4-14 PYR-GLN-PHE-PHE-GLY-LEU-MET-NH2 SEPTIDE PYR-MET-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-ILE-LEU-ASN-NH2 PYR-PHE-PHE-GLY-LEU-MET-NH2 Pyr3] – beta – Amyloid (3 – 40),Human (D-Asp1)-Amyloid β-Protein (1-42) (Gly22)-Amyloid β-Protein (1-42) β-Amyloid (18-28) β-Amyloid (13-27) β- Amyloid (1-34) β- Amyloid (4-10) AMYLOID BETA-PROTEIN (1-38) (Gln)-Amyloid β-Protein (1-40) AMYLOID BETA-PROTEIN (33-42)

  • [PYR3]-BETA-AMYLOID (3-42)
  • (GLP3) BETA-AMYLOID (3-42)
  • (PYR3)-AMYLOID BETA-PROTEIN (3-42)
  • [PYR3]-AMYLOID BETA-PROTEIN (HUMAN, 3-42) TRIFLUOROACETATE
  • PYR-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
  • PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE
  • (Pyr3)-Amyloid β-Protein
  • (PGLU3)-AMYLOID BETA-PROTEIN*FRAGMENT (3-42)
  • [pglu3]-amyloid β-protein fragment 3-42
  • (Pyr3)-AMyloid b-Protein (3-42)
  • Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
  • Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val
  • AβPE3-42
  • PYR-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA TRIFLUOROACETATE USP/EP/BP
  • pGlu3]-Amyloid β-Protein Fragment 3-42
  • (Pyr3)-Amyloid β-Protein (3-42) ammonium salt
  • Pyr3] β- Amyloid (3-42), human-10140-001
  • Pyr3] β- Amyloid (3-42), human
  • (Pyr?)-Amyloid β-Protein (3-42) ammonium salt
  • [Pyr3]-Amyloid β-Protein (Human, 3-42) (0.5 mg vial)
  • (Pyr3)-Amyloid B-protein (3-42) trifluoroacetate
  • [Pyr3]-Beta-Amyloid-Protein (3-42)
  • (Pyr3)-β-Amyloid(3-42)
  • 183449-57-2
  • C196H299N53O55S
  • C196H299N53O55S1
  • Neurodegenerative Disease Peptides
  • Peptides
  • Biochemicals and Reagents
  • Amyloid beta Protein Fragments
  • Amino Acids and Peptides
  • BioChemical
  • peptide
  • Alzheimers and Neurodegenerative Disease Research
  • Amyloid beta Protein Fragments
  • Amyloid β Protein FragmentsNeuropeptides
  • Neurodegenerative Disease Peptides
  • β Amyloid Peptides