ChemicalBook > CAS DataBase List > N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT

N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT

Product Name
N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT
CAS No.
24967-27-9
Chemical Name
N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT
Synonyms
N-ACETYL-2 3-DEHYDRO-2-DEOXYNEURAMINIC &;2-deoxy-2,3-dehydro-n-acetylneuraminicacid;N-ACETYL-2,3-DEHYDRO-2-DEOXYNEURAMINIC ACID;2,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID;1,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID;N-acetyl-2,3-didehydro-2-deoxyneuraminic acid;2,3-Dehydro-2-deoxy-N-acetylneuraminic Acid DANA;N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid >N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid >=93%;N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid
CBNumber
CB1280913
Molecular Formula
C11H17NO8
Formula Weight
291.25
MOL File
24967-27-9.mol
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N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT Property

Melting point:
227-228
Boiling point:
773.4±60.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: soluble50mg/mL, clear, colorless
pka
3.90±0.70(Predicted)
form 
Solid
color 
White to Pale Yellow
biological source
synthetic (organic)
optical activity
[α]20/D 40.8 to 51.0 °, c =0.66% (w/v) in water
Water Solubility 
water: 1mM
BRN 
8722455
CAS DataBase Reference
24967-27-9
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
3-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D9050
Product name
N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid
Purity
≥93%
Packaging
5mg
Price
$149.24
Updated
2025/07/31
Sigma-Aldrich
Product number
D9050
Product name
N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid
Purity
≥93%
Packaging
10mg
Price
$281
Updated
2025/07/31
Cayman Chemical
Product number
19939
Product name
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid
Purity
≥95%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19939
Product name
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid
Purity
≥95%
Packaging
5mg
Price
$116
Updated
2024/03/01
Sigma-Aldrich
Product number
D9050
Product name
N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid
Purity
≥93%
Packaging
25mg
Price
$558
Updated
2025/07/31
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N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT Chemical Properties,Usage,Production

Uses

Neuraminidase (sialidase) inhibitor

Uses

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt is a bacterial, viral, and mammalian neuraminidase inhibitor. It can be used in biological study of knockdown of Neu4 and injection of sialidase inhibitor such as DANA resulted in impairment of long-term potentiation at mossy fiber-CA3 synapses and hippocampus-dependent spatial memory in rats.

Definition

ChEBI: N-Acetylneuraminic acid reduced across the 2,3-bond with loss of the hydroxy group at C-2; it is a minor component of body fluids although abundant in sialuria.

Biological Activity

Inhibitor of bacterial, viral and animal neuraminidase (sialidase).

in vivo

N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) (10 mg/kg; i.p.; daily) attenuates pulmonary fibrosis in a mouse model[3].

Animal Model:Mice (Mouse model of pulmonary fibrosis)[3]
Dosage:10?mg/kg
Administration:I.p.; daily (starting at day 10 after Bleomycin, and then euthanized at day 21)
Result:Inhibition of sialidases starting at day 10 after bleomycin attenuates fibrosis.

N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT manufacturers

Career Henan Chemical Co
Product
N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT 24967-27-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10t
Release date
2019-12-20

24967-27-9, N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALTRelated Search:


  • 2-deoxy-2,3-dehydro-n-acetylneuraminicacid
  • N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT
  • N-ACETYL-2,3-DEHYDRO-2-DEOXYNEURAMINIC ACID
  • N-ACETYL-2,3-DEHYDRO-2-DEOXYNEURAMINIC ACID SODIUM SALT
  • 1,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID
  • 2,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID
  • N-acetyl-2,3-didehydro-2-deoxyneuraminic acid
  • N-ACETYL-2 3-DEHYDRO-2-DEOXYNEURAMINIC &
  • 2,3-Dehydro-2-deoxy-N-acetylneuraminic Acid DANA
  • <i>N</i>-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid
  • N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid, >98.0%(HPLC)
  • (4S,5R,6R)-5-ACETAMIDO-4-HYDROXY-6-[(1R,2R)-1,2,3-TRIHYDROXYPROPYL]-5,6-DIHYDRO-4H-PYRAN-2-CARBOXYLI
  • (2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
  • N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid &gt
  • D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-
  • 2,3 Dehydro 2 deoxy N acetylneuraminic acid,2,3Dehydro2deoxyNacetylneuraminic acid
  • N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid >=93%
  • 24967-27-9
  • C11H17NO8
  • BioChemical
  • Biochemicals and Reagents
  • Carbohydrates
  • Monosaccharide
  • Pharm intermediate
  • Intermediates