EQUISETIN
- Product Name
- EQUISETIN
- CAS No.
- 57749-43-6
- Chemical Name
- EQUISETIN
- Synonyms
- LS-64262;EQUISETIN;Citalopram Impurity 39;(3E,5S)-3-[[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(E)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione;2,4-Pyrrolidinedione, 5-(hydroxymethyl)-3-[hydroxy[(1S,2R,4aS,6R,8aR)-1,2,4a,5,6,7,8,8a-octahydro-1,6-dimethyl-2-(1E)-1-propen-1-yl-1-naphthalenyl]methylene]-1-methyl-, (3E,5S)-;(3E,5S)-3-{[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
- CBNumber
- CB1281192
- Molecular Formula
- C22H31NO4
- Formula Weight
- 373.49
- MOL File
- 57749-43-6.mol
EQUISETIN Property
- Melting point:
- 117-118 °C
- Boiling point:
- 556.0±50.0 °C(Predicted)
- Density
- 1.180±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.50±1.00(Predicted)
- color
- Pale Beige to Light Brown
- Stability:
- Hygroscopic
Safety
- HS Code
- 29339900
- Toxicity
- mouse,LD50,intraperitoneal,63mg/kg (63mg/kg),Antimicrobial Agents and Chemotherapy. Vol. 5, Pg. 634, 1974.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- 18196
- Product name
- Equisetin
- Purity
- ≥99%
- Packaging
- 1mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 18196
- Product name
- Equisetin
- Purity
- ≥99%
- Packaging
- 5mg
- Price
- $684
- Updated
- 2024/03/01
- Product number
- E3450-55
- Product name
- Equisetin
- Packaging
- 1mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- E592900
- Product name
- Equisetin
- Packaging
- 0.5mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- API0016732
- Product name
- EQUISETIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.9
- Updated
- 2021/12/16
EQUISETIN Chemical Properties,Usage,Production
Description
Equisetin is a fungal metabolite that has been isolated from Fusarium. It inhibits HIV-1 integrase 3’ end-processing and strand transfer activities. Equisetin inhibits the ATPase activity of rat liver mitochondria and mitoplasts stimulated by 2,4-dinitrophenol (Dnp) in a concentration-dependent manner (IC50 = ~8 nM per mg of protein for both). It also inhibits ADP-stimulated respiration and the mitochondrial transport of ATP, inorganic phosphate, and succinate. Epiequisetin is phytotoxic and inhibits the germination of various seeds and growth of young seedlings.
Uses
The tetramic acid, equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against HIV-1 integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3' end-processing and strand transfer, as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core.
Uses
Equisetin is tetramic acid with antibiotic and cytotoxic activity, and a potent inhibitor of HIV-1 integrase.
EQUISETIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from EQUISETIN manufacturers
- Product
- EQUISETIN 57749-43-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25