5-(4-NITROPHENYL)-2-FUROIC ACID
- Product Name
- 5-(4-NITROPHENYL)-2-FUROIC ACID
- CAS No.
- 28123-73-1
- Chemical Name
- 5-(4-NITROPHENYL)-2-FUROIC ACID
- Synonyms
- NPFA;AKOS BB-8339;ASISCHEM T31195;ART-CHEM-BB B025354;RARECHEM AL BE 0741;5-(4-NITROPHENYL)-2-FUROIC ACID;5-(4-Nitrophenyl)-2-furoic acid 96%;5-(4-nitrophenyl)-2-furancarboxylate;5-(4-NITROPHENYL)-2-FURANCARBOXYLIC ACID;5-(4-Nitrophenyl)-furane-2-carboxylic acid
- CBNumber
- CB1286399
- Molecular Formula
- C11H7NO5
- Formula Weight
- 233.18
- MOL File
- 28123-73-1.mol
5-(4-NITROPHENYL)-2-FUROIC ACID Property
- Melting point:
- 255-257 °C (dec.)(lit.)
- Boiling point:
- 451.4±35.0 °C(Predicted)
- Density
- 1.440±0.06 g/cm3(Predicted)
- pka
- 2.80±0.10(Predicted)
- InChI
- InChI=1S/C11H7NO5/c13-11(14)10-6-5-9(17-10)7-1-3-8(4-2-7)12(15)16/h1-6H,(H,13,14)
- InChIKey
- FXZTYDPWMQBTDH-UHFFFAOYSA-N
- SMILES
- O1C(C2=CC=C([N+]([O-])=O)C=C2)=CC=C1C(O)=O
- CAS DataBase Reference
- 28123-73-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 428558
- Product name
- 5-(4-Nitrophenyl)-2-furoic acid
- Purity
- 96%
- Packaging
- 1g
- Price
- $63.5
- Updated
- 2026/03/19
- Product number
- N497198
- Product name
- 5-(4-Nitrophenyl)furan-2-carboxylicAcid
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- N497198
- Product name
- 5-(4-Nitrophenyl)furan-2-carboxylicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 0607AQ
- Product name
- 5-(4-Nitrophenyl)-2-furoic acid
- Packaging
- 1g
- Price
- $112
- Updated
- 2021/12/16
- Product number
- CHM0012416
- Product name
- 5-(4-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1004.85
- Updated
- 2021/12/16
5-(4-NITROPHENYL)-2-FUROIC ACID Chemical Properties,Usage,Production
Uses
5-(4-Nitrophenyl)-2-furoic acid (5-(p-nitrophenyl)-2-furoic acid) is a 5-aryl-2-furoic acid. It is a dantrolene metabolite and its presence in plasma and urine has been determined by HPLC. It was reported to be the only product formed during the reduction of 5-(4-nitrophenyl)-2-furaldehyde by modified Cannizzaro reaction.
Synthesis Reference(s)
[1] Mori, M.;Tresoldi, A.; Villa, S.;Cazzaniga, G.;Bellinzoni, M.;Meneghetti, F.5-(4-Nitrophenyl)furan-2-carboxylic Acid. Molbank 2022, 2022, M1515.
General Description
5-(4-Nitrophenyl)-2-furoic acid (5-(p-nitrophenyl)-2-furoic acid) is a 5-aryl-2-furoic acid. It is a dantrolene metabolite and its presence in plasma and urine has been determined by HPLC. It was reported to be the only product formed during the reduction of 5-(4-nitrophenyl)-2-furaldehyde by modified Cannizzaro reaction.
Synthesis
To a solution of methyl 5-(4-nitrophenyl)furan-2-carboxylate (2, 50 mg, 0.2 mmol) in a mixture of H2O (2.6 mL) and MeOH (1.3 mL) was added NaOH (24 mg, 0.6 mmol). The reaction mixture was stirred at reflux for 3 h and partially concentered in vacuo to remove the solvent; then, 1 M HCl was added to adjust the pH to 3–4. The aqueous phase was extracted with EtOAc (3 × 5 mL), the combined organic phases were dried over anhydrous Na2SO4, filtered, and evaporated under reduced pressure to obtain 5-(4-NITROPHENYL)-2-FUROIC ACID as a yellow solid.[1]
5-(4-NITROPHENYL)-2-FUROIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-(4-NITROPHENYL)-2-FUROIC ACID manufacturers
- Product
- 5-(4-NITROPHENYL)-2-FUROIC ACID 28123-73-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11