ChemicalBook > CAS DataBase List > 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
- Product Name
- 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
- CAS No.
- 171268-84-1
- Chemical Name
- 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
- Synonyms
- 3'-TBS-OMe-rU;3'-TBDMS-2'-O-Me-rU;3'-O-TBDMS-2'-OME-U;3'-O-TBDMS-2'-OMe-Ur;3'-O-TBDMS-2'-O-methyluridine;3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine;3’-O-(t-Butyldimethylsilyl)-2’-O-methyluridine;3'-O-(tert-Butyldimethylsilyl)-2'-O-methyluridine;3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine;Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-
- CBNumber
- CB13035253
- Molecular Formula
- C16H28N2O6Si
- Formula Weight
- 372.49
- MOL File
- 171268-84-1.mol
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3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Property
- Density
- 1.20±0.1 g/cm3(Predicted)
- pka
- 9.39±0.10(Predicted)
- InChI
- InChI=1S/C16H28N2O6Si/c1-16(2,3)25(5,6)24-12-10(9-19)23-14(13(12)22-4)18-8-7-11(20)17-15(18)21/h7-8,10,12-14,19H,9H2,1-6H3,(H,17,20,21)/t10-,12-,13-,14-/m1/s1
- InChIKey
- VWMFRWSCFRRALN-FMKGYKFTSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1O[Si](C(C)(C)C)(C)C
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3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Chemical Properties,Usage,Production
Uses
3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
References
[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Preparation Products And Raw materials
Raw materials
Preparation Products
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