3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine

Product Name: 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
CAS No.: 171268-84-1
Chemical Name: 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
Synonyms: 3'-TBS-OMe-rU;3'-TBDMS-2'-O-Me-rU;3'-O-TBDMS-2'-OME-U;3'-O-TBDMS-2'-OMe-Ur;3'-O-TBDMS-2'-O-methyluridine;3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine;3’-O-(t-Butyldimethylsilyl)-2’-O-methyluridine;3'-O-(tert-Butyldimethylsilyl)-2'-O-methyluridine;3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine;Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-
CBNumber: CB13035253
Molecular Formula: C16H28N2O6Si
Formula Weight: 372.49
MOL File: 171268-84-1.mol

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3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Property

Density: 1.20±0.1 g/cm3(Predicted)
pka: 9.39±0.10(Predicted)
InChI: InChI=1S/C16H28N2O6Si/c1-16(2,3)25(5,6)24-12-10(9-19)23-14(13(12)22-4)18-8-7-11(20)17-15(18)21/h7-8,10,12-14,19H,9H2,1-6H3,(H,17,20,21)/t10-,12-,13-,14-/m1/s1
InChIKey: VWMFRWSCFRRALN-FMKGYKFTSA-N
SMILES: OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1O[Si](C(C)(C)C)(C)C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Chemical Properties,Usage,Production

Uses

3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

References

[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5

3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine Suppliers

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171268-84-1, 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridineRelated Search:

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171268-84-1