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Peucedanocoumarin III

Product Name
Peucedanocoumarin III
CAS No.
130464-57-2
Chemical Name
Peucedanocoumarin III
Synonyms
Peucedanocoumarin III;(2E)-2-Methyl-2-butenoic acid (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester;2-Butenoic acid, 2-methyl-, (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester, (2E)-
CBNumber
CB13037459
Molecular Formula
C21H22O7
Formula Weight
386.4
MOL File
130464-57-2.mol
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Peucedanocoumarin III Property

Boiling point:
486.8±45.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Hazard and Precautionary Statements (GHS)

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Peucedanocoumarin III Chemical Properties,Usage,Production

Description

Peucedanocoumarin Ⅲ can induce rice resistance to blast disease.

Uses

Peucedanocoumarin III is an inhibitor of (alpha)-synuclein and Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins (i.e., mutant Huntington proteins and α-synuclein). Peucedanocoumarin III may be used in Parkinson's disease research[1].

IC 50

α-synuclein Aggregation

References

[1] Sangwoo Ham, et al. Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates. Mol Cells. 2019 Jun 30;42(6):480-494. DOI:10.14348/molcells.2019.0091

Peucedanocoumarin III Preparation Products And Raw materials

Raw materials

Preparation Products

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Peucedanocoumarin III Suppliers

Sichuan Wei Keqi Biological Technology Co., Ltd.
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EMMX Biotechnology LLC
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130464-57-2, Peucedanocoumarin IIIRelated Search:


  • Peucedanocoumarin III
  • (2E)-2-Methyl-2-butenoic acid (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester
  • 2-Butenoic acid, 2-methyl-, (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester, (2E)-
  • 130464-57-2