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Axitinib Impurity D

Product Name
Axitinib Impurity D
CAS No.
1443118-72-6
Chemical Name
Axitinib Impurity D
Synonyms
AxitinibG;Axitinib Impurity D;Acitinib impurity 10;N-methyl-2-[3-[(E)-2-pyridin-2-ylethenyl]-1-(2-pyridin-2-ylethyl)indazol-6-yl]sulfanylbenzamide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-[2-(2-pyridinyl)ethyl]-1H-indazol-6-yl]thio]-;Axitinib Impurity 8/(E)-N-methyl-2-(1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)benzamide;(E)-N-Methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide (Axitinib Impurity)
CBNumber
CB13038986
Molecular Formula
C29H25N5OS
Formula Weight
491.61
MOL File
1443118-72-6.mol
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Axitinib Impurity D Property

Boiling point:
734.9±60.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
pka
14.44±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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Axitinib Impurity D Chemical Properties,Usage,Production

Uses

(E)-N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide is an metabolite of Axitinib(A794650) which is is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.

Axitinib Impurity D Preparation Products And Raw materials

Raw materials

Preparation Products

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1443118-72-6, Axitinib Impurity DRelated Search:


  • Axitinib Impurity 8/(E)-N-methyl-2-(1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)benzamide
  • N-methyl-2-[3-[(E)-2-pyridin-2-ylethenyl]-1-(2-pyridin-2-ylethyl)indazol-6-yl]sulfanylbenzamide
  • AxitinibG
  • Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-[2-(2-pyridinyl)ethyl]-1H-indazol-6-yl]thio]-
  • (E)-N-Methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide (Axitinib Impurity)
  • Axitinib Impurity D
  • Acitinib impurity 10
  • 1443118-72-6