ChemicalBook > CAS DataBase List > DC_517

DC_517

Product Name
DC_517
CAS No.
500017-70-9
Chemical Name
DC_517
Synonyms
DC_517;CS-2082;DC_517 (DC-517);2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-
CBNumber
CB13041399
Molecular Formula
C33H35N3O2
Formula Weight
505.65
MOL File
500017-70-9.mol
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DC_517 Property

Boiling point:
727.9±60.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 50 mg/mL (98.88 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
13.88±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-4587
Product name
DC_517
Purity
99.66%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-4587
Product name
DC_517
Purity
99.66%
Packaging
10mg
Price
$720
Updated
2021/12/16
ChemScene
Product number
CS-4587
Product name
DC_517
Purity
99.66%
Packaging
50mg
Price
$2160
Updated
2021/12/16
Crysdot
Product number
CD31001760
Product name
DC_517
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
Crysdot
Product number
CD31001760
Product name
DC_517
Purity
98+%
Packaging
10mg
Price
$416
Updated
2021/12/16
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DC_517 Chemical Properties,Usage,Production

Uses

DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively.

IC 50

DNMT1: 0.91 μM (Kd); DNMT1: 1.7 μM (IC50)

References

[1] Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-9041. DOI:10.1021/jm501134e

DC_517 Preparation Products And Raw materials

Raw materials

Preparation Products

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DC_517 Suppliers

China 23 United States 7 Global 30
Haoyuan Chemexpress Co., Ltd.
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500017-70-9, DC_517Related Search:


  • CS-2082
  • DC_517 (DC-517)
  • DC_517
  • 2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-
  • 500017-70-9