STING-Inducer-1
- Product Name
- STING-Inducer-1
- CAS No.
- 1638241-89-0
- Chemical Name
- STING-Inducer-1
- Synonyms
- MIW815;ML RR-S2 CDA;STING-Inducer-1;ML RR-S2 CDA(MIW815;ADUS100,ADU S100,ADU-S-100;ML RR-S2 CDA;MIW815;STING-INDUCER-1;ML RR-S2 CDA;STING-INDUCER-1;1638241-89-0;Adenosine, [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-, cyclic nucleotide
- CBNumber
- CB13041465
- Molecular Formula
- C20H24N10O10P2S2
- Formula Weight
- 690.54
- MOL File
- 1638241-89-0.mol
STING-Inducer-1 Property
- Boiling point:
- 1020.8±75.0 °C(Predicted)
- Density
- 2.43±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 2 mg/mL (2.90 mM)
- form
- Solid
- pka
- -0.67±0.70(Predicted)
- color
- White to off-white
- InChI
- InChI=1/C20H24N10O10P2S2/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(32)13-8(38-19)2-36-42(34,44)40-14-11(31)7(1-35-41(33,43)39-13)37-20(14)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,43)(H,34,44)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11?,12-,13-,14-,19-,20-,41-,42-/s3
- InChIKey
- IZJJFUQKKZFVLH-UUXHIKLWNA-N
- SMILES
- OC1([H])[C@@]2([H])CO[P@](O[C@@]3([H])[C@@H](O)[C@H](N4C=NC5=C(N=CN=C45)N)O[C@]3([H])CO[P@](S)(=O)O[C@@]1([H])[C@H](N1C=NC3=C(N=CN=C13)N)O2)(S)=O |&1:3,7,9,11,13,25,29,33,35,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-4197
- Product name
- ADU-S100
- Purity
- 99.53%
- Packaging
- 1mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- FM166994
- Product name
- ML RR-S2 CDA
- Packaging
- 1mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- CS-4197
- Product name
- ADU-S100
- Purity
- 99.53%
- Packaging
- 5mg
- Price
- $645
- Updated
- 2021/12/16
- Product number
- FM166994
- Product name
- ML RR-S2 CDA
- Packaging
- 2mg
- Price
- $820
- Updated
- 2021/12/16
- Product number
- CS-4197
- Product name
- ADU-S100
- Purity
- 99.53%
- Packaging
- 10mg
- Price
- $1150
- Updated
- 2021/12/16
STING-Inducer-1 Chemical Properties,Usage,Production
Uses
ML-RR-S2-CDA is a stimulator of interferon genes (STING) agonist for cancer treatment.
Biological Activity
ADU-S100 (MIW815) is an activator of stimulator of interferon genes (STING) with potent antitumor and immune activity.
in vivo
ADU-S100 shows higher anti-tumor control than the endogenous ML cGAMP. A dose response of the ADU-S100 compound is performed in B16 tumor-bearing mice, which identifies an optimal antitumor dose level that also elicites maximum tumor antigen-specific CD8 + T cell responses, and improves long-term survival to 50%.
target
STING
STING-Inducer-1 Preparation Products And Raw materials
Raw materials
Preparation Products
STING-Inducer-1 Suppliers
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29763
- Advantage
- 68
- Tel
- 0530-+86-530-529 6766,+86-15666160102 15666160102
- Fax
- 0530-529 6766
- info@chuangli-chem.com
- Country
- China
- ProdList
- 839
- Advantage
- 55
- Tel
- +1-800-259-7612
- Fax
- +1-800-259-7612
- info@musechem.com
- Country
- United States
- ProdList
- 4660
- Advantage
- 60
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9729
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32159
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9409
- Advantage
- 58
- Tel
- 13969155946
- 1461866103@qq.com
- Country
- China
- ProdList
- 16111
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 020-82000279 18988968278
- Fax
- QQ:3283937693
- YN_research@163.com
- Country
- China
- ProdList
- 2869
- Advantage
- 58
- Tel
- 021-38015121 18438616290
- wulan@absin.cn
- Country
- China
- ProdList
- 24731
- Advantage
- 58