Fevipiprant

Product Name: Fevipiprant
CAS No.: 872365-14-5
Chemical Name: Fevipiprant
Synonyms: QAW039;CS-2449;NVP-QAW039;Fevipipran;Fevipiprant;NVP-QAW039;QAW039;Fevipiprant (QAW039);Fevipiprant(NVP-QAW039);Fevipiprant, 10 mM in DMSO;NVP-QAW039; QAW039;QAW039;QAW-039;QAW 039;FEVIPIPRANT
CBNumber: CB13054555
Molecular Formula: C19H17F3N2O4S
Formula Weight: 426.41
MOL File: 872365-14-5.mol

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Fevipiprant Property

Boiling point:: 637.6±55.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 10 mg/mL; DMF:PBS(pH7.2) (1:2): 0.33 mg/mL; DMSO: 10 mg/mL; Ethanol: 1 mg/mL
form: A crystalline solid
pka: 3.33±0.30(Predicted)
color: White to off-white
InChI: InChI=1S/C19H17F3N2O4S/c1-11-15(9-17(25)26)14-4-3-7-23-18(14)24(11)10-12-5-6-13(29(2,27)28)8-16(12)19(20,21)22/h3-8H,9-10H2,1-2H3,(H,25,26)
InChIKey: GFPPXZDRVCSVNR-UHFFFAOYSA-N
SMILES: C12N(CC3=CC=C(S(C)(=O)=O)C=C3C(F)(F)F)C(C)=C(CC(O)=O)C1=CC=CN=2

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20263
Product name: Fevipiprant
Purity: ≥98%
Packaging: 500μg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 20263
Product name: Fevipiprant
Purity: ≥98%
Packaging: 1mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 20263
Product name: Fevipiprant
Purity: ≥98%
Packaging: 5mg
Price: $467
Updated: 2024/03/01

TRC

Product number: F321755
Product name: Fevipiprant
Packaging: 1mg
Price: $65
Updated: 2021/12/16

Apolloscientific

Product number: BISN0035
Product name: Fevipiprant
Purity: 99%
Packaging: 1mg
Price: $66
Updated: 2021/12/16

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Fevipiprant Chemical Properties,Usage,Production

Uses

Fevipiprant is used in the oral treatment of asthma and has been successful in targeting severe eosinophilic asthma.Fevipiprant is a novel oral prostaglandin D2 receptor 2 (DP2; known as CRTh2) antagonist and currently in development for the treatment of severe asthma and atopic dermatitis.

in vivo

Fevipiprant (10 mg/kg; in the drinking water) reduces CaCl2-induced AAA (abdominal aortic aneurysm) formation in mouse^[3].

Animal Model:	C57Bl/6 mice^[3]
Dosage:	10 mg/kg
Administration:	In the drinking water
Result:	Efficiently reduced CaCl2-induced AAA formation with diminished elastin degradation, aortic macrophage infiltration, MPO accumulation and MCP-1 expression.

IC 50

DP2: 1.14 nM (Kd)

Fevipiprant Preparation Products And Raw materials

Raw materials

Preparation Products

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Fevipiprant Suppliers

China 103 India 2 United Kingdom 1 United States 9 Global 115

Shanghai Zhengyi Pharmaceutical Co., Ltd

Tel: 17740884366
Email: derek1229@163.com
Country: China
ProdList: 61
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Country: China
ProdList: 1112
Advantage: 64

Wuhan Vanzpharm Inc.

Tel: 027-84492310 13657243668
Fax: 027-84492310
Email: wangting@vanzpharm.com
Country: China
ProdList: 50
Advantage: 58

Shanghai AQBioPharma Co., Ltd.

Tel: 13661411401
Fax: 51370935-8011
Email: yinglv.que@aqbiopharma.com.cn
Country: China
ProdList: 2930
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14917
Advantage: 59

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4795
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 983
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 5307
Advantage: 55

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9295
Advantage: 55

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View Lastest Price from Fevipiprant manufacturers

Wuhan Nutra Biotechnology Co.,Ltd

Product: fevipiprant;NVP-QAW039 872365-14-5
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 98%
Supply Ability: 100kgs
Release date: 2021-05-23

Dingwang Technology (Wuhan) Co., Ltd.

Product: Fevipiprant 872365-14-5
Price: US $2300.00-16200.00/gram
Min. Order: 10gram
Purity: 99%
Supply Ability: 20 tons
Release date: 2022-10-31

Zhuozhou Wenxi import and Export Co., Ltd

Product: Fevipiprant 872365-14-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

872365-14-5, FevipiprantRelated Search:

QAW039

Fevipiprant

Fevipipran

NVP-QAW039

Fevipiprant(NVP-QAW039)

Fevipiprant (QAW039)

2-Methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridine-3-acetic acid

NVP-QAW039; NVP-QAW 039; NVP-QAW-039 QAW-039; QAW039; QAW 039; FEVIPIPRANT

CS-2449

NVP-QAW039; QAW039;QAW039;QAW-039;QAW 039;FEVIPIPRANT

NVP-QAW039;QAW039

1H-Pyrrolo[2,3-b]pyridine-3-acetic acid, 2-methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-

2-[2-methyl-1-[[4-methylsulfonyl-2-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridine-3-yl]acetic acid

Fevipiprant, 10 mM in DMSO

872365-14-5