Bis-PEG1-PFP ester
- Product Name
- Bis-PEG1-PFP ester
- CAS No.
- 1807539-02-1
- Chemical Name
- Bis-PEG1-PFP ester
- Synonyms
- PFP-PEG1-PFP;Bis-PEG1-PFP ester;Bis(perfluorophenyl) 3,3'-Oxydipropanoate;3,3'-Oxydipropanoic acid dipentafluorophenyl ester;Propanoic acid, 3,3'-oxybis-, 1,1'-bis(2,3,4,5,6-pentafluorophenyl) ester;2,3,4,5,6-pentafluorophenyl 3-[3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propoxy]propanoate
- CBNumber
- CB13062408
- Molecular Formula
- C18H8F10O5
- Formula Weight
- 494.24
- MOL File
- 1807539-02-1.mol
Bis-PEG1-PFP ester Property
- Boiling point:
- 452.6±45.0 °C(Predicted)
- Density
- 1.609±0.06 g/cm3(Predicted)
- solubility
- Soluble in DCM
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-21833
- Product name
- Bis-PEG1-PFPester
- Purity
- 98%
- Packaging
- 5G
- Price
- $1750
- Updated
- 2021/12/16
Bis-PEG1-PFP ester Chemical Properties,Usage,Production
Description
Bis-PEG1-PFP ester is a PEG linker with two PFP ester moieties. The PFP ester is amine-reactive, stable compound. PFP esters are less susceptible toward hydrolysis compared to NHS esters. The PEG linker increases the water solubility of compounds in aqueous environments.
Uses
Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Non-cleavable Linker
References
[1] CORTEZ, Alex, et al. ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST. WO2017072662A1.
Bis-PEG1-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
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