Bromoacetamido-PEG5 -Azide
- Product Name
- Bromoacetamido-PEG5 -Azide
- CAS No.
- 1415800-37-1
- Chemical Name
- Bromoacetamido-PEG5 -Azide
- Synonyms
- Bromoacetamido-PEG5-N3;Bromoacetamide-PEG5-azide;Bromoacetamido-PEG5 -Azide;N-(17-Azido-3,6,9,12,15-pentaoxaheptadecyl)-2-bromoacetamide;N-(17-azido-3,6,9,12,15-pentaoxaheptadecan-1-yl)-2-bromoacetamide;N-(2-[2-(2-(2-[2-(2-Azidoethoxy)ethoxy]ethoxy)ethoxy)ethoxy]ethyl)-2-bromoacetamide
- CBNumber
- CB13062433
- Molecular Formula
- C14H27BrN4O6
- Formula Weight
- 427.3
- MOL File
- 1415800-37-1.mol
Bromoacetamido-PEG5 -Azide Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Viscous Liquid
- color
- Colorless to light yellow
Safety
- HS Code
- 2929900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- A965735
- Product name
- N-(2-[2-(2-(2-[2-(2-Azidoethoxy)ethoxy]ethoxy)ethoxy)ethoxy]ethyl)-2-bromoacetamide
- Packaging
- 25mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- BP-21097
- Product name
- Bromoacetamido-PEG5-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BIPG1314
- Product name
- Bromoacetamido-PEG5 -Azide
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
- Product number
- BP-21097
- Product name
- Bromoacetamido-PEG5-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $810
- Updated
- 2021/12/16
Bromoacetamido-PEG5 -Azide Chemical Properties,Usage,Production
Description
Bromoacetamido-PEG5-azide is a heterobifunctional crosslinking reagent. The bromide (Br) is a very good leaving group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG spacer increases solubility in aqueous media.
Uses
Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromoacetamido-PEG5 -Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromoacetamido-PEG5 -Azide Suppliers
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 400-8592883
- Fax
- 0731-82251112
- sales@huatengsci.com
- Country
- China
- ProdList
- 5873
- Advantage
- 58
- Tel
- 0431-80534353 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3828
- Advantage
- 55
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32469
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 1996
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39927
- Advantage
- 58
View Lastest Price from Bromoacetamido-PEG5 -Azide manufacturers
- Product
- BrCH2CONH-PEG5-N3 1415800-37-1
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-25